Unravelling the role of WRKY transcription factors in leaf senescence: Genetic and molecular insights.

Background: Leaf senescence (LS), the final phase in leaf development, is an important and precisely regulated process crucial for plant well-being and the redistribution of nutrients. It is intricately controlled by various regulatory factors, including WRKY transcription factors (TFs). WRKYs are one of the most significant plant TF families, and several of them are differentially regulated and important during LS.

Enhancing Withanolide Production in the Species: Advances in In Vitro Culture and Synthetic Biology Approaches.

Withanolides are naturally occurring steroidal lactones found in certain species of the genus, especially (commonly known as Ashwagandha). These compounds have gained considerable attention due to their wide range of therapeutic properties and potential applications in modern medicine. To meet the rapidly growing demand for withanolides, innovative approaches such as in vitro culture techniques and synthetic biology offer promising solutions.

In vitro study: methylene blue-based antibacterial photodynamic inactivation of Pseudomonas aeruginosa.

Pseudomonas aeruginosa is one of the most antibiotic-resistant and opportunistic pathogens in immunocompromised and debilitated patients. It is considered the cause of most severe skin infections and is frequently found in hospital burn units. Due to its high antibiotic resistance, eliminating P.

Attenuation of quorum sensing regulated virulence functions and biofilm of pathogenic bacteria by medicinal plant Artemisia annua and its phytoconstituent 1, 8-cineole.

The emergence of multidrug resistance (MDR) in bacterial pathogens is a serious public health concern. A significant therapeutic target for MDR infections is the quorum sensing-regulated bacterial pathogenicity. Determining the anti-quorum sensing abilities of certain medicinal plants against bacterial pathogens as well as the in-silico interactions of particular bioactive phytocompounds with QS and biofilm-associated proteins were the objectives of the present study.

Rhubarb: A novel model plant to study the conundrum of calcium oxalate synthesis.

The study investigated calcium oxalate (CaOx) crystal composition, accumulation, synthesis, and degradation in five rhubarb species from the North-Western Indian Himalayas. Techniques like optical and scanning electron microscopy (SEM), SEM-energy-dispersive X-ray spectroscopy (SEM-EDS), inductively coupled plasma-optical emission spectrometry (ICP-OES), X-ray diffraction spectroscopy (XRD), and real-time (qRT-PCR) expression analysis of strategic genes were used to understand the processes of oxalate synthesis and precipitation. Results showed crystals tend to accumulate around vascular bundles in all species, irrespective of size, indicating a consistent pattern.

Association of TGF-β1 Polymorphism and TGF-β1 Levels With Chronic Hepatitis C and Cirrhosis: A Systematic Review and Meta-Analysis.

Despite the extensive research conducted on the relationship between transforming growth factor-beta 1 (TGF-β1) polymorphisms and levels and the onset and development of liver disease, there are still certain gaps that need to be addressed. To address these gaps and provide a comprehensive overview of the current knowledge, this review aimed to identify relevant published research on TGF-β1/TGF-β1 polymorphism, TGF-β1/TGF-β1 levels, and their associations with cirrhosis and hepatitis C. The synthesis of available data was performed to further enhance our understanding in this area.

Self-assembled and Zn(II)-coordinated dipeptide nanoparticles with membrane-rupturing action on bacteria.

Metal ion-coordinated self-assembled short-chain amino acid peptide molecules with multi-photon excitation wavelengths and their photoluminescence properties are advantageous for fluorescence-based diagnostics and treatments of biological diseases based on their extra features of antibacterial agents. We have designed a novel strategy based on tryptophan molecule coordinated with Zn(II) ions in the form of biocompatible spherical nanoparticles of diameter 30-80 nm which have been used for antibacterial treatments against different kinds of pathogenic bacteria (Escherichia coli, Salmonella typhimurium, and Pseudomonas). Preferably, we have used tryptophan-phenylalanine (Trp-Phe), a dipeptide molecule having tryptophan as principal material against E.

Spiritual intelligence and psychological wellbeing of Pakistani University students.

The objective of this study was to find out the predictive role of spiritual intelligence for psychological wellbeing in university students and also to assess gender differences. For that reason, data of = 250 ( = 21.8; = 1.

Validation of conventional and synchronous fluorescence emission of potable water.

Water from filter plants and bottled water is generally safe to drink but regular quality monitoring of these facilities requires development of quick analytical technique to ensure public safety and health. This study presented the variation of two components in spectra of conventional fluorescence spectroscopy (CFS) and four components in synchronous fluorescence spectroscopy (SFS) to assess the quality of 25 water samples from different sources. Poor quality water either due to organic or inorganic contaminants presented high intensity fluorescence emission in the blue green region and low intensity water Raman peak unlike an intense water Raman peak originated from pure water when excited at 365 nm.

Third International Conference on Medical Education and Medical writing, University of Karbala College of Medicine, Karbala, Iraq.

University of Karbala College of Medicine (UKCM), Iraq, conducted a three days' workshop on Medical Education and medical writing. The UKCM is now transforming to conform with the latest trends of modern education. This will help to re-shape the future of medical education and produce capable doctors.

High-performance terahertz refractive index sensor for cancer cells detection.

Metamaterial absorbers in the terahertz region are highly desirable in sensing and detection. In this work, a novel terahertz refractive index sensor based on metamaterial absorber for sensing biomedical samples is reported. The proposed structure consists of three asymmetrical metallic resonators made of gold placed above on a gallium arsenide (GaAs) dielectric layer.

Gold nanocubes based optical detection of HIV-1 DNA via surface enhanced Raman spectroscopy.

Optical detection of HIV-1 DNA with surface enhanced Raman spectroscopy (SERS) is a quick and versatile method, having great potential in screening and characterization of HIV-1 virus particle. We have synthesized and applied novel gold nanocubes (AuNCs) for signal enhancement of SERS to study HIV-1 DNA strands by taking into account the specific vibrational bands of functional groups. Raman peaks at 562 cm, 800 cm, 1094 cm were observed in both Human Random Control DNA and HIV-1 DNA, while three new peaks were detected in infected DNA at 421 cm, 1069 cm and 1254 cm.

An integrated model of UTAUT2 to understand consumers' 5G technology acceptance using SEM-ANN approach.

It has been a decade since the first extensive study on the internet's adoption and use was conducted. Circumstances have changed in the last decade internet has become an essential need for every human being. Socio-psychological, economic, and personal factors play a significant role in shaping human behaviour.

Biotechnological Intervention and Secondary Metabolite Production in L.

L., commonly known as Gotu kola, Indian pennywort, and Asiatic pennyworts, is an herbaceous perennial plant that belongs to the family Apiaceae and has long been used in the traditional medicine system. The plant is known to produce a wide range of active metabolites such as triterpenoids including asiatic acid, asiaticoside, brahmoside, and madecassic acid along with other constituents including centellose, centelloside, and madecassoside, etc.

Designing a clean environmental framework for Pakistan: analyzing the nonlinear impact of aggregate demand drivers on CO2 emissions.

Aggregate demand in every country is one of the main components of macroeconomics, and Pakistan is no exception. This paper uses a fresh econometric framework to analyze the nonlinear impact of aggregate demand drivers on CO emissions in Pakistan by using a nonlinear ARDL approach over the data period from 1975 to 2019. The linear findings reveal that consumption and government expenditure indicates deteriorating effects on carbon emissions in long run in Pakistan.

Anti-quorum sensing, antibiofilm, and antibacterial activities of extracts of L. leaves, and derived leaves-calli through tissue culture: a potential for biofouling-prevention.

Extracts of leaves (LEs), and leaf-calli (CEs), were investigated for antibacterial, antibiofilm, and anti-quorum sensing activities. Ethyl acetate extracts from leaves (EALE), leaf-calli (EACE), methanolic extracts from leaves (MELE), and leaf-calli (MECE) showed antibacterial activity; the minimum inhibitory concentrations (MICs) of LEs and CEs ranged from 0.312-2.

Micropropagation, encapsulation, physiological, and genetic homogeneity assessment in .

is an important tree of the forest, cultivated in tropical and subtropical regions, providing fuelwood, land reclamation, dune stabilization, paper production, and nitrogen fixation. We have developed a systematic propagation protocol in using nodal segments (NS). Murashige and Skoog (MS) medium augmented with BA (5.

Nanotechnological Interventions in Agriculture.

Agriculture is an important sector that plays an important role in providing food to both humans and animals. In addition, this sector plays an important role in the world economy. Changes in climatic conditions and biotic and abiotic stresses cause significant damage to agricultural production around the world.

Does an Adjustable-Loop Device Loosen following ACL Reconstruction with a Hamstring Graft? A Retrospective Study with a Follow-Up of Two Years.

Arthroscopic anatomic anterior cruciate ligament reconstruction (ACLR) is the gold standard treatment for an ACL tear and requires the use of fixed or adjustable-loop devices to fix a femoral-side graft. Although the adjustable mechanism is designed to provide one-way tensioning, there is a concern that the adjustable loop will loosen and lengthen during cyclic loads, creating graft laxity. The present paper is a retrospective study of patients who underwent ACLR with the fixation of a hamstring graft with an adjustable loop on the femoral side from November 2016 to October 2018.

Task allocation in multi-robot system using resource sharing with dynamic threshold approach.

Task allocation is a fundamental requirement for multi-robot systems working in dynamic environments. An efficient task allocation algorithm allows the robots to adjust their behavior in response to environmental changes such as fault occurrences, or other robots' actions to increase overall system performance. To address these challenges, this paper presents a Task Allocation technique based on a threshold level which is an accumulative value aggregated by a centralized unit using the Task-Robot ratio and the number of the available resource in the system.