Bitis arietans, or the puff adder, has venom that causes significant pain and organ damage, and this study explores its effects on liver and kidney inflammation in rats.
The research involved administering a controlled dose of BAV to rats and analyzing their blood and tissue samples over time to observe changes in inflammatory markers and organ function.
Results indicated that a single low dose of BAV triggered acute inflammation in the liver and kidneys, with certain proinflammatory cytokines (like IL-1β, IL-6, and TNF-α) showing increased levels shortly after exposure, suggesting that higher doses could lead to more serious and lasting organ damage.