Accelerated Discovery of the Polymer Blends for Cartilage Repair through Data-Mining Tools and Machine-Learning Algorithm.

In designing successful cartilage substitutes, the selection of scaffold materials plays a central role, among several other important factors. In an empirical approach, the selection of the most appropriate polymer(s) for cartilage repair is an expensive and time-consuming affair, as traditionally it requires numerous trials. Moreover, it is humanly impossible to go through the huge library of literature available on the potential polymer(s) and to correlate the physical, mechanical, and biological properties that might be suitable for cartilage tissue engineering.

Statistical and Machine Learning-Driven Optimization of Mechanical Properties in Designing Durable HDPE Nanobiocomposites.

The selection of nanofillers and compatibilizing agents, and their size and concentration, are always considered to be crucial in the design of durable nanobiocomposites with maximized mechanical properties (i.e., fracture strength (FS), yield strength (YS), Young's modulus (YM), etc).

On the Injection Molding Processing Parameters of HDPE-TiO₂ Nanocomposites.

In recent years, the development and use of polymeric nanocomposites in creating advanced materials has expanded exponentially. A substantial amount of research has been done in order to design polymeric nanocomposites in a safe and efficient manner. In the present study, the impact of processing parameters, such as, barrel temperature, and residence time on the mechanical and thermal properties of high density polyethylene (HDPE)-TiO₂ nanocomposites were investigated.

Polymeric nanobiocomposites for biomedical applications.

Polymeric nanobiocomposites have recently become one of the most essential sought after materials for biomedical applications ranging from implants to the creation of gels. Their unique mechanical and biological properties provide them the ability to pass through the highly guarded defense mechanism without undergoing noticeable degradation and initiation of immune responses, which in turn makes them advantageous over the other alternatives. Aligned with the advances in tissue engineering, it is also possible to design three-dimensional extracellular matrix using these polymeric nanobiocomposites that could closely mimic the human tissues.