Publications by authors named "Anurodh Gupta"
Article Synopsis
- MicroRNAs play a crucial role in regulating gene expression and are linked to various diseases, prompting a study to find specific serum miRNAs associated with prediabetes in patients with alcohol dependence syndrome (ADS).
- Researchers compared serum samples from ADS patients (both with and without prediabetes) to healthy controls and validated their findings using RT-qPCR and pathway analyses.
- The study identified significantly different expressions of numerous miRNAs, with hsa-miR-320b and hsa-miR-3135b being particularly notable as potential biomarkers for diagnosing prediabetes in ADS patients.
Development and validation of LCMS method for determination of Ethyl Glucuronide (EtG) in urine.
Med J Armed Forces India
July 2022
Background: Ethyl glucuronide (EtG) is a phase II metabolite of ethanol and is an upcoming biomarker for recent alcohol intake. Monitoring of alcohol intake in case of alcohol-dependent syndrome is very useful for early intervention and preventing harmful effects. EtG has also been identified as a very useful marker in differentiating antemortem ingestion of alcohol from postmortem production of alcohol.
View Article and Find Full Text PDFIdiopathic retinal vasculitis is a chronic disease of unknown aetiology which results in ocular morbidity in patients of productive age group. Homocysteine has been implicated in various ocular conditions like age-related macular degeneration, retinal vein occlusions, diabetic retinopathy, and optic nerve diseases. We conducted a study to investigate the relation between serum homocysteine levels and retinal vasculitis at a tertiary care centre in North India.
View Article and Find Full Text PDFEarly diagnosis of SARS-CoV-2 infected patients is essential to control the dynamics of the COVID-19 pandemic. We develop a rapid and accurate one-step multiplex TaqMan probe-based real-time RT-PCR assay, along with a computational tool to systematically analyse the data. Our assay could detect to a limit of 15 copies of SARS-CoV-2 transcripts-based on experiments performed by spiking total human RNA with synthesized viral transcripts.
View Article and Find Full Text PDFBackground: The mortality and morbidity rates are two to fourfold higher among Coronary Artery Disease (CAD) patients with type 2 diabetes mellitus (DM). American Diabetes Association (ADA) and World Health Organization (WHO) define different criteria for the diagnosis of glucose intolerance. This study compares the available diagnostic criteria for DM in Indian men and their importance in CAD patients.
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