Publications by authors named "Anurag Sachan"

Article Synopsis
  • * Out of 82 patients, a significant number did not respond to steroid treatment, but the baseline histological scores did not show a strong association with the need for second-line therapy or colectomy.
  • * The conclusion suggests that these histological scores are not reliable predictors for treatment needs in ASUC, prompting a call for further research on their long-term impact.
View Article and Find Full Text PDF

Introduction: Patients with ulcerative colitis (UC) are likely to have poor nutritional intake and increased gut losses. This study was designed to study the prevalence and predictors of nutritional deficiencies in patients with UC and their impact on the quality of life (QOL).

Methods: A prospective study was conducted among consenting patients with UC (cases) and healthy relatives of the cases (controls) visiting a university teaching hospital.

View Article and Find Full Text PDF

Endoscopic retrograde cholangiopancreatography (ERCP) is the workhorse for biliary and pancreatic ductal interventions. Despite advances in both endoscopes and accessories for ERCP, it still has limitations in the presence of altered anatomy, luminal obstruction hindering access to the papilla, and proximal duct obstructions by tight stricture, calculi or intraductal growth. Endoscopic ultrasound-guided biliary drainage (EUS-BD) and EUS-guided pancreatic duct drainage (EUS-PDD) have expanded the rescue procedures after failed ERCP.

View Article and Find Full Text PDF

Background And Aim: Discrimination of gastrointestinal tuberculosis (GITB) and Crohn's disease (CD) is difficult. Use of artificial intelligence (AI)-based technologies may help in discriminating these two entities.

Methods: We conducted a systematic review on the use of AI for discrimination of GITB and CD.

View Article and Find Full Text PDF
Article Synopsis
  • Jejunal gastrointestinal stromal tumours (GIST) are rare tumors that can cause serious bleeding, leading to complex diagnostic and treatment situations in emergencies.
  • A retrospective analysis was conducted on three patients who experienced acute bleeding from confirmed jejunal GIST, detailing their clinical signs, diagnostic imaging results, and surgical outcomes.
  • Multiphasic Computed Tomographic Angiography was effective in identifying the tumors, and surgical resection proved to be the best treatment for controlling the bleeding and ensuring clear margins; most patients had favorable outcomes post-surgery.
View Article and Find Full Text PDF

Background: Traditionally peptic ulcer disease was the most common cause of upper gastrointestinal (UGI) bleed but with the changing epidemiology; other etiologies of UGI bleed are emerging. Many scores have been described for predicting outcomes and the need for intervention in UGI bleed but prospective comparison among them is scarce.

Objective: This study was planned to determine the etiological pattern of UGI bleed and to compare Glasgow Blatchford score, Pre-Endoscopy Rockall score, AIMS65, and Modified Early Warning Score (MEWS) as predictors of outcome.

View Article and Find Full Text PDF

Background And Aims: Endoscopic dilation is an important therapeutic option for treatment of corrosive strictures. Its safety is unclear with variable perforation rates in previous studies. We aimed to evaluate its safety with regard to perforations and the effect of dilator type to perforation risk.

View Article and Find Full Text PDF

Objectives: Healthcare personnel (HCP) are at an increased risk of acquiring COVID-19 infection especially in resource-restricted healthcare settings, and return to homes unfit for self-isolation, making them apprehensive about COVID-19 duty and transmission risk to their families. We aimed at implementing a novel multidimensional HCP-centric evidence-based, dynamic policy with the objectives to reduce risk of HCP infection, ensure welfare and safety of the HCP and to improve willingness to accept and return to duty.

Setting: Our tertiary care university hospital, with 12 600 HCP, was divided into high-risk, medium-risk and low-risk zones.

View Article and Find Full Text PDF