Beneath the surface: unveiling the gut-brain axis in anorexia and depression.

Anorexia nervosa (AN) and depression are complex conditions with high comorbidity, impacting mental and physical health. Recent research suggests gut microbiota plays a significant role in their development and progression. This correspondence highlights the critical gaps in understanding the gut-brain axis in AN and depression, emphasizing the need for comprehensive research.

When surgery leaves more than just scars: The curious case of gossypiboma- A case report and literature review.

Gossypiboma is a unique postoperative complication characterized by the presence of a surgical sponge after surgery. This condition is seldom encountered. Owing to its serious medicolegal implications it remains underreported leading to a blurred clinical spectrum.

Clinical Profile and Endoscopic Management in Patients with Choledocholithiasis.

Background: Common bile duct stones is a common medical problem that are usually seen in association with gallstone disease. Endoscopic management of Common bile duct stones involves doing Endoscopic retrograde cholangiography for bile duct clearance which is the primary therapeutic modality of choice. This prospective study was done to identify the clinical characteristics and outcome of patients presenting with Common bile duct stones undergoing Endoscopic retrograde cholangiography.

Post-cholecystectomy clip migration: an unusual nidus of choledocholithiasis: a case report.

Introduction And Importance: Laparoscopic cholecystectomy is one of the common surgeries occurring worldwide and the gold standard for the management of gallstone disease. The non-absorbable surgical clips may slip and can migrate causing a variety of problems as such, choledocholithiasis.

Case Presentation: The authors report a case of 43-year-old female who presented with the complaint epigastric pain.

Comparison of Acute Physiology and Chronic Health Evaluation II, Bedside Index for Severity in Acute Pancreatitis and Modified Computed Tomography Severity Index Scores in Predicting the Outcome in Acute Pancreatitis in a Tertiary Care Centre in Nepal.

Background: It is important to identify the severity of acute pancreatitis in the early course of the disease.

Methods: This prospective observational study included 83 patients with acute pancreatitis. The Acute Physiology and Chronic Health Evaluation II and the Bedside Index for Severity in Acute Pancreatitis scores were assessed within 24 hours of admission, and the modified computed tomography severity index score was calculated in those patients who underwent contrast enhanced computed tomography.

Detection of Colonic Polyps During Colonoscopy in a Tertiary Care Center of Nepal.

Background: Colorectal cancer is the third leading cause of cancer death in the world. Most colon cancer develop from the polyps. Data on the prevalence of colorectal polyps in Nepal is lacking.

Comparative Study of Slow Infusion versus Bolus Doses of Albumin and Furosemide Infusion to Mobilize Refractory Ascites in Decompensated Chronic Liver Disease.

Background: Combined use of furosemide with albumin is an approved therapy to overcome diuretic resistance in treatment of ascites in decompensated chronic liver disease. Bolus dosing of diuretics has its own limitations due to pre-existing hypotension, post diuretic sodium retention and braking phenomenon. Slow albumin and furosemide Infusion has been shown to mobilize large ascites with improved diuresis and hemodynamic stability in decompensated chronic liver disease.