Homocysteine and nutritional biomarkers in cognitive impairment.

Cognitive impairment is a progressive disorder that affects the ageing population. With the increase in the mean age of our population, it is becoming a public health problem. Homocysteinemia has been implicated in cognitive impairment.

Fluidized Immobilized Carbon Catalytic Oxidation Reactor for Treating Domestic Wastewater.

Treating wastewater and reusing it have become normal in the present era since the scarcity of fresh water prevails in many parts of the world. There are numerous techniques for treating domestic wastewater, and many have been explored to advance the ones already in use. This study is taken up to explore the new technology called .

Effectiveness of COVID-19 Vaccines against SARS-CoV-2 Infection among Persons Attending the RT-PCR center at a Medical College Hospital in Telangana: A Case- Control Study.

Background: In January 2021, India's drug regulator issued restricted emergency approval for COVISHIELD and COVAXIN, which were manufactured in India. In mid-January 2021, in India, there were 10.5 million confirmed cases and 0.

A Comparative Evaluation of Anesthetic Effectiveness of 4% Articaine vs 0.5% Bupivacaine for Lower Molar Tooth Extraction.

Background: Safe and efficient pain control is essential for today's dental practice. This randomized controlled study was conducted to evaluate the effectiveness of 0.5% bupivacaine with 4% articaine in lower molar tooth extraction.

Influence of tebuconazole and copper hydroxide on phosphatase and urease activities in red sandy loam and black clay soils.

The efficacy of two selected fungicides i.e., tebuconazole and coppoer hydroxide, was conducted experiments in laboratory and copper hydroxide on the two specific enzymes phosphatase and urease were determined in two different soil samples (red sandy loam and black clay soils) of groundnut (Arachis hypogaea L.

Evaluation of Anti-Inflammatory Effects of Curcumin Gel as an Adjunct to Scaling and Root Planing: A Clinical Study.

Background: Complete removal of irritants is not possible with mechanical therapy alone. Adjunctive use of systemic administration of antibiotics results in the distribution of drug throughout the body, which can give rise to toxicity. Curcumin (diferuloylmethane), a constituent of Curcuma longa plant, which possess antioxidant, anti-inflammatory, anti-carcinogenic, anti-microbial, anti-hyper algesic and hypocholesterolemic properties.

Oral and salivary changes in patients with chronic kidney disease: A clinical and biochemical study.

Background: Both chronic kidney disease (CKD) and its treatment can affect a wide range of tissues and systems. It directly or indirectly affects flow, concentrations and composition of saliva. Hemodialysis can effectively minimize most of these complications to some extent.

Application of 810-nm diode laser in the management of peripheral ossifying fibroma.

Peripheral ossifying fibroma (POF) is a reactive gingival growth, which accounts for 9.6% of gingival lesions. It exhibits a peak incidence between the second and third decades of life with a female predilection.

Assessment of palatal masticatory mucosa: a cross-sectional study.

Aim: To treat mucogingival problems palatal masticatory mucosa is used as a donor material. This study aimed to determine the thickness of donor palatal mucosa and associations of age and gender in Indian subjects aged 14 to 60 years by direct clinical technique.

Materials And Methods: Forty systemically and periodontally healthy Indian subjects (20 males; 20 females; age range of 14 to 60 years) enrolled in this study.

Filariasis of the breast--an unusual presentaion.

Filariasis of the breast presenting as a breast lump and clinically simulating as breast tumour is an unusual presentation. The present case is of a 30 years old female complaining of breast lump and on fine needle aspiration revealed microfilaria.

Clinical evaluation of intrabony defects in localized aggressive periodontitis patients with and without bioglass- an in-vivo study.

Background: Aggressive periodontitis is a specific type of periodontitis with clearly identifiable clinical characteristics such as rapid attachment loss, bone destruction and familial aggregation. Regeneration of mineralized tissues affected by aggressive periodontitis comprises a major scientific and clinical challenge. In recent years some evidence has been provided that bioactive glass is also capable of supporting the regenerative healing of periodontal lesions.

Seropositivity of toxoplasmosis in antenatal women with bad obstetric history in a tertiary-care hospital of Andhra Pradesh, India.

Toxoplasmosis is a well-documented cause of bad obstetric history (BOH) and a major reason of congenitally-acquired infection. The study was conducted to determine the seropositivity of toxoplasmosis in women with BOH, attending the antenatal clinic of the Mamata General Hospital, Khammam, Andhra Pradesh, India. The study subjects included 105 antenatal women with BOH and 105 antenatal women who had previous normal deliveries.

Prevalence of dental caries among 13 and 15-year-old school children in an endemic fluorosis area: a cross-sectional study.

Aim: To assess the prevalence of dental caries and dental fluorosis among 13- to 15-year-old school children in Panyam, Andhra Pradesh, India.

Materials And Methods: The cross-sectional study was conducted among 202 school children and were examined for dental fluorosis and dental caries.

Results: This study shows that male students have a decrease in DMFT (Decayed, missing, filled, teeth) index and increase in Dean's index when compared with females.

In vitro levels of interleukin 10 (IL-10) and IL-12 in response to a recombinant 32-kilodalton antigen of Mycobacterium bovis BCG after treatment for tuberculosis.

Cell-mediated immunity plays a major role in conferring protection against tuberculosis (TB) on an individual. It is not known whether the immune status correlates with the bacterial load or whether the immunity improves after treatment. Also, it may be important to monitor treatment by being able to discriminate between active disease and successfully treated TB.

Interferon-gamma Low producer genotype +874 overrepresented in Bacillus Calmette-Guerin nonresponding children.

Background: There are limited reports on the influence of the immune regulatory genotypes on the efficacy of Bacillus Calmette-Guerin (BCG) in man. This study was designed to evaluate the influence of the cytokine genotype interferon (IFN)-gamma +874T/A on T cell in vitro assays in BCG nonresponders (negative to either in vivo or in vitro test with purified protein derivative or both).

Methods: Ninety healthy children who were without any clinical evidence of the disease, 45 with a BCG-scar and the remaining 45 without scar were assessed for in vitro T cell responses.

Age-related waning of in vitro Interferon-gamma levels against r32kDaBCG in BCG vaccinated children.

Background: Mycobacterium bovis BCG vaccine has displayed inconsistent efficacy in different trials conducted in various geographical regions. Nevertheless, it significantly reduces the risk of severe childhood tuberculosis and continues to be used to prevent tuberculosis in many countries. Many studies revealed that efficacy of vaccine wanes with age.

Prevalence of drug resistance under the DOTS strategy in Hyderabad, South India, 2001-2003.

Background: Multidrug-resistant tuberculosis (MDR-TB), defined as resistance to at least isoniazid (INH) and rifampicin (RMP), is considered a threat to TB control. Implementation of DOTS ensures high cure rates and prevents MDR.

Objective: To study the prevalence of MDR-TB from a retrospective analysis of the data in a tuberculosis unit where DOTS was implemented over a period of 6 years through public private mix (PPM).

Activities of glucose-metabolizing enzymes in experimental neurotoxic models with lipoate as an alleviator.

Acrylamide (35 mg kg(-1) body wt, i.p.) and mercuric chloride (1 mg kg(-1)body wt, i.

Protective role of DL-alpha-lipoic acid against mercury-induced neural lipid peroxidation.

Experimental neurotoxicity in rat models was induced by an intramuscular injection of mercuric chloride. dl-alpha-lipoic acid was administered as an antidote in three protocols of experimental design. Two protocols of short-term exposure of mercury was designed, one with prophylactic therapy and the other with curative therapy of lipoic acid.

Degree of peroxidative status in neuronal tissues by different routes of inorganic mercury administration.

Mercuric chloride was administered by three routes--subcutaneous, intramuscular and intraperitoneal to adult female Wistar rats. The peroxidative status of the cerebral cortex, cerebellum and the sciatic nerves were studied. Enhanced levels of lipid peroxides indicate progressing cellular injury.