Utilization of cassava peel based cellulose nanofiber for developing functionalized pectin/pullulan/olive oil nanocomposite film for cling wrapping of chicken meat.

The current research focused on the utilization of cassava peel for fabricating cellulose nanofiber (CNF) and development of nanocomposite films for cling wrapping of chicken meat. The extraction of cellulose was achieved through the pretreatment method of cassava peel. Further, CNF was fabricated via acid hydrolysis (HSO) of cassava peel derived cellulose.

Fine Tuning of Electrical Characteristics of Inkjet Printed Graphene for Physical and Chemical Sensing.

This study highlights the versatile applications of inkjet-printed graphene/ethyl cellulose (EC) in various electronic devices. Key points include its p-type doping achieved through low-temperature annealing, its use as a temperature sensor at higher annealing temperatures, and its effectiveness in electrochemical sensing, such as phosphate detection. The precise tuning of the oxygen composition of EC in graphene via thermal annealing was crucial to these capabilities.

Early Haploidentical Hematopoietic Stem Cell Transplantation Provides Rapid Leukocyte and Immune Reconstitution in AK2 Patient Identified by TREC Newborn Screening.

Reticular dysgenesis (RD) is a rare inborn error of immune cell formation defined by severe combined immunodeficiency, agranulocytosis and sensorineural deafness. We report a case of successful haploidentical maternal hematopoietic stem cell transplantation (HSCT) in a boy with RD detected by TREC newborn screening. The patient was admitted to our hospital at 2 weeks of age and was kept in laminar-air flow / hepa-filtered isolation until HSCT was performed at 8 weeks of age with a busulfan, fludarabine conditioning regime.

Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida.

The aging process is universal, and it is characterized by a progressive deterioration and decrease in physiological function leading to decline on the organismal level. Nevertheless, a number of genetic and non-genetic interventions have been described, which successfully extend healthspan and lifespan in different species. Furthermore, a number of clinical trials have been evaluating the feasibility of different interventions to promote human health.

Begomovirus capsid proteins interact with cyclic adenosine monophosphate (cAMP)-specific phosphodiesterase of its whitefly vector and modulate virus retention within its vector.

Unlabelled: Begomoviruses are whitefly-transmitted ss-DNA viruses that infect dicotyledonous plants and contribute to major economic losses to global crop production. Invasion and establishment of an aggressive cryptic species of , known as the B cryptic species, has severely constrained vegetable production in the southeastern and southwestern United States. Disruption of genes/pathways critical for whitefly-mediated transmission can be effective for the management of begomoviruses.

Genomic hallmarks of endocrine therapy resistance in ER/PR+HER2- breast tumours.

ER/PR+HER2- breast tumours are the most predominant subtype of breast cancer worldwide, including India. Unlike TNBCs, these tumours can be treated with anti-estrogens or aromatase inhibitors. Despite the success of endocrine therapy, a fraction of patients with ER/PR+ breast tumours do not respond to hormone-receptor-specific treatment and encounter disease recurrence contributing to their poor survival.

Thermal processing to modulate surface chemistry and bulk charge distribution in nickel-rich layered lithium positive electrodes.

The broader application of nickel-rich layered oxides as positive electrode materials for lithium-ion batteries has been hindered by their high manufacturing cost and inferior cycling stability. Thermal processing, which is integral to electrode materials manufacturing and fundamental in materials science, has not been fully utilized to design advanced positive electrode materials. Herein, we demonstrate the capability of using quenching heat treatment to regulate Li distribution and modulate electronic structure near particle surface.

Production, radiochemical separation and electrochemical concentration of No-carrier-added Mn: An emerging PET radiometal.

Recently, there has been significant interest in Mn (T = 5.6 d) as a relatively long lived radiometal for PET imaging of cancer. In this study, we have produced Mn from natural Cr metallic powder target via Cr (p, n) Mn reaction in a particle accelerator.

Particulate toxic elements' oxidative potential and gastrointestinal bioaccessibility features in the vicinities of coal-fired mineral processing industries, India.

Particulate matter (PM) poses significant health risks due to its ability to generate reactive oxygen species (ROS) and transport toxic metal(loid)s into the human body. In this study, an in vitro physiologically based extraction test (PBET) method, allowing the simulation of the gastric phase (GPh) and intestinal phase (IPh) of human digestion, was applied to evaluate bioaccessibility of eleven potentially toxic elements (Al, As, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn) in airborne particulate matter (APM) samples collected from an urban-residential area in Chhattisgarh, India. Additionally, oxidative potential (OP) was assessed using the dithiothreitol (DTT) assay for a comprehensive understanding of PM toxicity.

Ball-milled Ni@MoC/C nanocomposites as efficient electrocatalysts for urea oxidation.

Urea oxidation reaction (UOR) has been identified as a promising method for hydrogen production and the remediation of urea-rich wastewater by electrochemical techniques. In the present work, Ni/C and Ni@MoC(x)/C electrocatalysts (x = 0.1, 0.

IFI16 recruits HDAC1 and HDAC2 to deacetylate the Kaposi's sarcoma-associated herpesvirus (KSHV) latency-associated nuclear antigen (LANA), facilitating latency.

Unlabelled: IFI16 (interferon-γ-inducible protein 16) is an innate-immune DNA sensor that detects viral dsDNA in the nucleus. It also functions as an antiviral restriction factor, playing a crucial role in regulating the latency/lytic balance of several herpesviruses, including Kaposi's sarcoma-associated herpesvirus (KSHV). We previously demonstrated that IFI16 achieves this by regulating the deposition of H3K9me3 marks on the KSHV genome.

Hypoelectronic titanaboranes: icosahedral and tetracapped tetrahedral clusters comprising bridging hydrides.

Unusual hypoelectronic -clusters, such as icosahedral [(Cp*Ti)(BH)(μ-H)(μ-Cl)] (1) and tetracapped tetrahedral [{(Cp*Ti)B}(μ-BH)(μ-Te)] (2), have been synthesized and structurally characterized. Clusters 1 and 2 represent the first examples of -titanaboranes having bridging hydrides, where the Ti⋯Ti interactions play a pivotal role in defining their shapes and electron counts. Furthermore, two face-fused clusters, [(Cp*Ti)(μ-Se)(μ-SePh)(μ-η:η-BHR)] (3a: R = H; 3b: R = Ph), have been isolated that deviate from Mingos fusion formalism.

Nonempirical dielectric dependent hybrid as an accurate starting point for the single shot G0W0 calculation of chalcopyrite semiconductors.

The accuracy of quasiparticle corrections in a single-shot G0W0 calculation relies heavily on the preceding eigensystem of density functional theory (DFT). An incorrect energy spectrum obtained from the DFT calculation can result in an inaccurate quasiparticle G0W0 bandgap. This study explicitly investigates the bandgaps of chalcopyrite semiconductors within G0W0, considering various DFT approximations, including semilocal, hybrid, and nonempirical screened dielectric-dependent hybrid (DDH) as the starting point for G0W0 calculation.

Evaluation of Propolis, Aloe Vera Gel, Noni, Pomegranate Juice Natural Storage Medium for Management of Avulsed Teeth.

Objectives: To ascertain the effectiveness of propolis, aloe vera gel, noni, and pomegranate juice natural storage solution in preserving the vitality of avulsed teeth PDL cells.

Materials And Methods: Forty recently extracted human premolars that were recommended for orthodontic purposes were used in the current investigation. Each of the four storage medium groups (N = 10)-Group A: propolis, Group B: pomegranate juice, Group C: aloe vera, and Group D: noni-was assigned to them at random.

Comparative Analysis of Push-Out Bond Strength of Different Root Canal Sealers to Root Dentin.

Aim: The study's objective is to assess the bond strengths of four different endodontic sealers to root dentin using a push-out test technique.

Material And Method: Sixty single-rooted teeth were selected and decoronated. Canal instrumentation was done using rotary files and divided into four groups ( = 15) based on the sealer used.

Pyridyl Aroyl Hydrazone-Based Metal Complexes Showing a Ligand-Centered Metal-Assisted Pathway for Electrocatalytic Hydrogen Evolution.

In the past few decades, the concern over the excessive use of fossil fuels and consequent environmental damage has triggered the search for cleaner and renewable energy resources. This has led to the consideration of hydrogen as our future fuel. It can be produced from various sources, and if used as fuel, it generates only water as a byproduct.

Unlocking the secrets of the human gut microbiota: Comprehensive review on its role in different diseases.

The human gut microbiota, a complex and diverse community of microorganisms, plays a crucial role in maintaining overall health by influencing various physiological processes, including digestion, immune function, and disease susceptibility. The balance between beneficial and harmful bacteria is essential for health, with dysbiosis - disruption of this balance - linked to numerous conditions such as metabolic disorders, autoimmune diseases, and cancers. This review highlights key genera such as , , , , , , (including and ), and due to their well-established roles in immune regulation and metabolic processes, but other bacteria, including , , , and , are also implicated in dysbiosis and various diseases.

The Impact of the COVID-19 Pandemic on Health and Health Care Experience in Those With Polycystic Ovary Syndrome.

Purpose: Polycystic Ovary Syndrome (PCOS) is a complex endocrine-metabolic disorder and is associated with a variety of health disorders. The management of PCOS requires a multidisciplinary health care approach. The COVID-19 pandemic affected access and delivery of health care.

Biocompatible glycolipid derived from bhilawanol as an antibiofilm agent and a promising platform for drug delivery.

Stimuli-responsive smart materials for biomedical applications have gained significant attention because of their potential for selectivity and sensitivity in biological systems. Even though ample stimuli-responsive materials are available, the use of traditional Ayurvedic compounds in the fabrication of pharmaceuticals is limited. Among various materials, gels are one of the essential classes because of their molecular-level tunability with little effort from the environment.

Genetic and biomarker disclosure process in a memory and aging study.

Despite growing awareness that disclosing biomarker results to research participants is aligned with ethical principles of researcher-participant partnership, there are currently no widely adopted guidelines for this disclosure in Alzheimer's disease research. We developed a process and tools to deliver biomarker and genetic results to 65 participants of The Memory and Aging Study of the Duke-UNC Alzheimer's Disease Research Center (ADRC). Survey responses of 46 participants were analyzed.

Effect of different pHs and liquid-to-solid ratios on leaching behavior of heavy metals from landfill-mined-soil-like-fractions.

The potential reuse of landfill-mined-soil-like-fractions (LFMSF), a significant by-product of landfill mining (LFM), is restricted due to the leaching of heavy metals (HMs). In this context, the present study assesses the leaching behavior of six HMs, i.e.

Fosamprenavir and Tirofiban to combat COPD and cancer: A drug repurposing strategy integrating virtual screening, MD simulation, and DFT studies.

Matrix metalloproteinases (MMPs) are involved in different pathophysiological conditions like cancer, COPD, asthma, and inflammatory diseases. Among these MMPs, macrophage metalloelastase is one of the prime targets for COPD, and cancer. Therefore, to combat such diseases, potent novel macrophage metalloelastase inhibitors can be considered.

The efficacies of degrading antibiotic resistance genes (ARGs) by applying UV light emitting diodes (UV-LEDs) based advanced oxidation processes (AOPs).

Widespread dissemination of antibiotic resistance genes (ARGs) in the aquatic environment has become a concern for public health. This study evaluated the performance of UV light emitting diodes (UV-LEDs) based advanced oxidation processes (AOPs) such as the simultaneous application of UV-LEDs (265 and 285 nm) and oxidants (chlorine and persulfate) to degrade ARGs. Persulfate (PS)-based treatment systems showed lower log-removals than chlorine (Cl) to degrade extracellular ARGs (e-ARGs), with the molar absorption coefficients (ɛ) for PS being 13.