Anemia in patients with hidradenitis suppurativa : A systematic review with meta-analysis.

Importance: Hidradenitis suppurativa (HS) is associated with a number of physical and psychological comorbidities. Studies have suggested an association between HS and anemia; however, this association is not widely understood and may result in delayed diagnosis and treatment and possible increase in morbidity and mortality.

Objective: To systematically review and perform a meta-analysis regarding the association between HS and anemia, and to characterize the subtypes of anemia associated with HS.

Synthesis and magnetic properties of manganese carbonyl complexes with different coordination modes of 3,4,5-triaryl-1,2-diphospholide ligands.

The set of complexes bis-(μ:η(1),η(1)-3,4,5-triaryl-1,2-diphosphacyclopentadienyl)-bis-(tetracarbonyl manganese(i)) (aryl = C6H5 (), p-FC6H4 (), p-ClC6H4 ()) undergo an irreversible rearrangement to mononuclear 3,4,5-triaryl-1,2-diphosphacymantrenes (). According to quantum-chemical calculations binuclear complexes can be considered to be products of kinetic control and mononuclear species are thermodynamically favorable compounds. The antiferromagnetic intramolecular interaction observed for complexes can be effectively tuned by using substituents in the para-position of the arene ring, whereas mononuclear 1,2-diphosphacymantrenes are diamagnetic.

Myeloid-derived suppressor cells modulate immune responses independently of NADPH oxidase in the ovarian tumor microenvironment in mice.

The phagocyte NADPH oxidase generates superoxide anion and downstream reactive oxidant intermediates in response to infectious threat, and is a critical mediator of antimicrobial host defense and inflammatory responses. Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid cells that are recruited by cancer cells, accumulate locally and systemically in advanced cancer, and can abrogate anti-tumor immunity. Prior studies have implicated the phagocyte NADPH oxidase as being an important component promoting MDSC accumulation and immunosuppression in cancer.

Interplay of magnetic exchange interactions and Ni-S-Ni bond angles in polynuclear nickel(II) complexes.

The ability of bridging thiophenolate groups (RS(-)) to transmit magnetic exchange interactions between paramagnetic Ni(II) ions is examined. Specific attention is paid to complexes with large Ni-SR-Ni angles. For this purpose, dinuclear [Ni(2)L(1)(mu-OAc)I(2)][I(5)] (2) and trinuclear [Ni(3)L(2)(OAc)(2)][BPh(4)](2) (3), where H(2)L(1) and H(2)L(2) represent 24-membered macrocyclic amino-thiophenol ligands, are prepared and fully characterized by IR- and UV/Vis spectroscopy, X-ray crystallography, static magnetization M measurements and high-field electron spin resonance (HF-ESR).