Publications by authors named "Anupama Chandrasekharan"

This observational study investigated the potential of radiomics as a non-invasive adjunct to CT in distinguishing COVID-19 lung nodules from other benign and malignant lung nodules. Lesion segmentation, feature extraction, and machine learning algorithms, including decision tree, support vector machine, random forest, feed-forward neural network, and discriminant analysis, were employed in the radiomics workflow. Key features such as Idmn, skewness, and long-run low grey level emphasis were identified as crucial in differentiation.

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In an observational study conducted from 2016 to 2021, we assessed the utility of radiomics in differentiating between benign and malignant lung nodules detected on computed tomography (CT) scans. Patients in whom a final diagnosis regarding the lung nodules was available according to histopathology and/or 2017 Fleischner Society guidelines were included. The radiomics workflow included lesion segmentation, region of interest (ROI) definition, pre-processing, and feature extraction.

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Objectives: Our aim is to describe the utility of magnetic resonance imaging (MRI) in the evaluation of pathologies affecting large intracranial arteries.

Materials And Methods: We performed a prospective and observational study from 2018 to 2020 using 1.5 T MRI.

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 The aim of the study is to assess the role of ultrafast (UF) magnetic resonance (MR) sequences in stroke imaging.  We prospectively studied 85 patients having clinical suspicion of stroke referred for MR imaging (MRI) during August 2016 to July 2018. These patients were subjected to both conventional and UF MRI sequences.

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Objective: The aim of this study is to compare the images obtained from standard ultrafast magnetic resonance (MR) imaging sequences with gradient (GRE) sequence images in identifying fetal intracranial hemorrhage (ICH).

Materials And Methods: MR images of fetal brains with ICH done between October 2012 and September 2015 were reviewed. The images obtained from four ultrafast MR sequences- Turbo Fast Low Angle Shot (Turbo FLASH) T1-weighted images, Half Fourier Acquisition single-shot turbo spin echo (HASTE) T2-weighted images, b0 images of diffusion-weighted imaging (DWI) and b800 images of DWI were compared with images obtained from GRE sequence in depicting fetal ICH.

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Preterm infants are at increased risk of adverse neurodevelopmental outcome (NDO). Cranial ultrasound has limited predictability. The purpose of the study is to evaluate whether magnetic resonance imaging (MRI) done at term equivalent age (TEA) predicts NDO at 18-22 months of corrected gestational age (CGA).

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Viral encephalitis by definition is the result of human virus affecting the brain and sparing the meninges. The other nervous system manifestations are meningitis, meningoencephalitis, encephalomyelitis, and encephalomyeloradiculitis. Encephalitis can involve any age group from children to old people.

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Background & Objectives: Renal artery stenosis (RAS) is an important cause of severe hypertension in patients with chronic kidney disease (CKD). It is important to detect RAS early as it can reverse hypertension and stop rapid deterioration of renal function. The potential drawbacks of various imaging modalities used to detect RAS including contrast-related adverse effects associated with diagnostic angiography have led to increasing interest in unenhanced magnetic resonance (MR) renal angiography.

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This review paper focuses on the neonatal brain segmentation algorithms in the literature. It provides an overview of clinical magnetic resonance imaging (MRI) of the newborn brain and the challenges in automated tissue classification of neonatal brain MRI. It presents a complete survey of the existing segmentation methods and their salient features.

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Unilateral agenesis of internal carotid artery (ICA) with intercavernous anastomosis is a rare congenital anomaly. We present a case of a 25-year-old female with 2-month history of holocranial headache. Neurological examination was unremarkable.

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Combination of middle and inner ear anomaly is extremely rare. We describe a case where there was inner and middle ear anomaly on the right side and inner ear anomaly on the left side. This patient also had anomalous interposition of air cells between the middle and inner ear on the right side which precluded the use of cochlear implant.

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Objectives: To evaluate the possible role of Magnetic Resonance (MR) signal intensity measurements in diagnosing Central Nervous System (CNS) anomalies antenatally.

Methods: MR images of 110 fetal brains between 18 and 38 weeks were studied. Nine were excluded due to destroyed brain.

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Decubital ischemic fasciitis, also called atypical decubital fibroplasia, is a distinctive fibroplasia occurring in nonambulatory older patients who are confined to bed or wheelchair-bound. These lesions are seen in the subcutaneous plane at pressure points or bony prominences. We present a case of ischemic fasciitis in a 68-year-old male patient who presented with a hard swelling in the middle third of the posterolateral aspect of the right leg, which is an unusual site for ischemic fasciitis.

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Congenital infiltrating lipomatosis of the face is a rare condition characterized by diffuse fatty infiltration of the facial soft tissues. There may be muscle involvement along with associated bony hyperplasia. It is a type of lipomatous tumor that is congenital in origin; it is rare and seen usually in childhood.

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Esophageal duplication cysts are classified as a subgroup of foregut duplication cysts. They are very rare and are predominantly detected in children. Antenatal detection is very rare.

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Objective: To compare antenatal sonography and magnetic resonance (MR) imaging (MRI) in the diagnosis of fetal head and trunk anomalies.

Methods: Forty pregnant women with fetal anomalies on ultrasound (US) examination underwent MRI. The MR examination was done by a radiologist who was provided with the US data.

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