Validation of Pefloxacin for detection of fluoroquinolone (FQ) resistance among Typhi with special reference to GyrB mutations.

Fluoroquinolone (FQ) resistant are classified as high priority pathogens by WHO. FQ resistance among Typhi has emerged rapidly and is predominantly mediated by mutations in the topoisomerase genes , and . Mutations in GyrA result in classical FQ resistance (DCS-NAR) i.