Publications by authors named "Anup Thorat"

Background: EMPOwER, a 12-week, double-blind (DB), randomized, placebo-controlled study evaluated the efficacy and safety of erenumab in adult patients with episodic migraine (EM) from Asia, the Middle East, and Latin America. This study analyzes the Indian experience for the use of erunumab for prevention of episodic migraine.

Objective: The study aimed to evaluate the efficacy and tolerability of erenumab (70 mg and 140 mg) in EM patients from India.

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Article Synopsis
  • Vildagliptin is a medication for type 2 diabetes available in two forms: a 50 mg immediate release (IR) taken twice daily and a new 100 mg modified release (MR) taken once daily.
  • A study compared the effectiveness and tolerability of these two formulations using healthy adults, with a focus on how well they inhibit the DPP-4 enzyme.
  • The results showed that both formulations are therapeutically equivalent for DPP-4 inhibition, suggesting that the once-daily MR version could improve patient adherence to treatment, although long-term safety remains to be assessed.
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Pain is most common symptom associated with progressive disorder, chronic kidney disease (CKD), and is usually undertreated during the early stages of CKD. So, present review was conducted to evaluate the challenges for the management of pain in CKD patients and addresses the scope for considering Diclofenac as suitable alternative for pain management in CKD patient. The database PubMed and Google Scholar were searched from 1970 to Dec 2020 for literature published in English and all studies, review articles that examined the use of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) in pain management in CKD patients were included.

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