Loop-Mediated Isothermal Loop-Mediated Isothermal Amplification (LAMP) is a widely used technique for nucleic acid amplification due to its high specificity, sensitivity, and rapid results. Advances in microfluidic lab-on-chip (LOC) technology have enabled the integration of LAMP into miniaturized devices, known as μ-LAMP, which require precise thermal control for optimal DNA amplification. This paper introduces a novel thermal bed design using PCB copper traces and FR-4 dielectric materials, providing a reliable, modular, and repairable heating platform.
View Article and Find Full Text PDFIn this work, we study a double-sense twisted low-birefringence Sagnac loop structure as a sound/vibration sensing device. We study the relation between the adjustments of a wave retarder inside the loop (which allows controlling the transmission characteristic to deliver 10, 100, and 300 μW average power at the output of the system) and the response of the Sagnac sensor to vibration frequencies ranging from 0 to 22 kHz. For a 300 m loop Sagnac, two sets of experiments were carried out, playing at the same time all the sound frequencies mixed for ∼1 s, and playing a sweep of frequencies for 30 s.
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