Comparing Single-Incision Cholecystectomy and Multiple-Incision Cholecystectomy: A Systematic Review and Meta-Analysis of Postoperative Complications.

Laparoscopic cholecystectomy is the gold standard for managing benign gallbladder disease, with the conventional multiport technique widely practiced. Single-incision laparoscopic cholecystectomy (SILC) has emerged as an alternative, offering potential benefits such as improved cosmetic outcomes, reduced pain, and quicker recovery; however, its efficacy and safety compared to conventional laparoscopic cholecystectomy (CLC) remain unclear. This meta-analysis, which followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, included 51 studies with 2,069 patients to compare clinical outcomes such as postoperative complications, pain, recovery time, and wound infection rates between SILC and CLC.