Local drug delivery for regeneration and disinfection in endodontics: A narrative review.

Local Drug Delivery Systems (LDDSs) represent a significant development in endodontic therapy, offering targeted, effective treatment options for managing root canal infections and regenerative outcomes. LDDS can be customized to deliver antimicrobial agents and/or bioactive components to the specific site to address challenges associated with resistant microbial species and enhance regenerative outcomes. Further research in this area is essential to optimize these systems to improve clinical success.