A novel lytic phage infecting MDR and its application as effective food biocontrol.

is a foodborne pathogen associated with both typhoid and non-typhoid illness in humans and animals. This problem is further exacerbated by the emergence of antibiotic-resistant strains of . Therefore, to meet public health and safety, there is a need for an alternative strategy to tackle antibiotic-resistant bacteria.

Phage Mediated Biocontrol: A Promising Green Solution for Sustainable Agriculture.

Unlabelled: In the current scenario of growing world population, limited cultivable land resources, plant diseases, and pandemics are some of the major factors responsible for declining global food security. Along with meeting the food demand, the maintenance of food quality is also required to ensure healthy consumption and marketing. In agricultural fields, pest infestations and bacterial diseases are common causes of crop damage, leading to massive yield losses.

Development and Evaluation of Bacteriophage Cocktail to Eradicate Biofilms Formed by an Extensively Drug-Resistant (XDR) .

Extensive and multiple drug resistance in combined with the formation of biofilms is responsible for its high persistence in nosocomial infections. A sequential method to devise a suitable phage cocktail with a broad host range and high lytic efficiency against a biofilm forming XDR strain is presented here. Out of a total thirteen phages isolated against , five were selected on the basis of their high lytic spectra assessed using spot assay and productivity by efficiency of plating assay.

Tracking the phage trends: A comprehensive review of applications in therapy and food production.

In the present scenario, the challenge of emerging antimicrobial resistance is affecting human health globally. The increasing incidences of multidrug-resistant infections have become harder to treat, causing high morbidity, and mortality, and are posing extensive financial loss. Limited discovery of new antibiotic molecules has further complicated the situation and has forced researchers to think and explore alternatives to antibiotics.

Synergy of a virulent phage (φAB182) with antibiotics leading to successful elimination of biofilms formed by MDR .

Emergence of multiple drug resistant (MDR) strains of and a withering drug discovery pipeline necessitates the search for effective alternatives to replace or synergize with currently used antibiotics. In this report, we have described the synergy assessment of a virulent phage φAB182 with a wide range of antibiotics. Myophage φAB182 was isolated from sewage against MDR and exhibited maximum stability at 25 °C and pH 7.