Publications by authors named "Anu Alex"

Background: The effects of noise on the vestibular and balance function are under-studied. Studies have demonstrated that like the cochlea, the otolith organs are also sensitive to sound but the exact mechanism is unclear. Both impulse and continuous noise exposure may damage the cochlear and/or vestibular organ and lead to the formation of endolymphatic hydrops.

View Article and Find Full Text PDF

Unlabelled: A randomized prospective parallel group trial was done to compare the efficacy of intratympanic low dose gentamicin with methylprednisolone in treating intractable unilateral Meniere's disease with serviceable hearing.

Study Design: Randomised prospective parallel group trial.

Setting: Tertiary care centre in South India.

View Article and Find Full Text PDF
Article Synopsis
  • The study compares the effectiveness of high-dose intratympanic gentamicin and methylprednisolone in treating unilateral Meniere's disease in patients with poor hearing.* -
  • A total of 22 patients participated, with 11 receiving gentamicin and 11 receiving methylprednisolone, and assessments were made pre-treatment, at 3 months, and in a follow-up period of 2-4 years.* -
  • Results showed that while both treatments reduced vertigo symptoms significantly, gentamicin provided better long-term outcomes for vertigo control and functional scores compared to methylprednisolone, with no significant difference in hearing levels between the two groups.*
View Article and Find Full Text PDF

A 42-year-old woman presented with fever, left ear pain, restricted mouth opening, difficulty in swallowing and inability to open her left eyelid for a period of 10 days. She was treated with antibiotics for the same at a local medical facility; however, a sudden decrease in her left eye vision prompted her to visit our tertiary centre. Her history was insignificant except for having multiple left ear syringing for an insect removal 10 days before onset of her current symptoms.

View Article and Find Full Text PDF

Context: Long-chain omega-3 polyunsaturated fatty acids (LCn-3PUFAs) are widely considered as nootropic agents that may be beneficial in reversing cognitive impairment.

Objective: The present systematic review of randomized controlled trials was conducted to determine the changes in cognitive function after intervention with LCn-3PUFA supplementation in non-demented adults, including those with mild cognitive impairment.

Data Sources: Five databases (MEDLINE, CINAHL, Scopus, EMBASE, and the Cochrane Library) were searched systematically along with reference lists of selected articles.

View Article and Find Full Text PDF

Third window defects have increasingly been identified as a cause of vertigo. These defects are bony dehiscences that occur in the bony labyrinth, resulting in abnormal pressure gradient in the inner ear fluids leading to sound (Tullio's phenomenon) or pressure (Hennebert's sign) induced vertigo. The superior semicircular canal dehiscence syndrome is a well-described entity in this regard, however defects of the posterior semicircular canal are rare and may have overlapping symptomatology.

View Article and Find Full Text PDF

Background & Aims: Chronic inflammation drives the development of insulin resistance and type 2 diabetes. Long-chain omega-3 polyunsaturated fatty acids (LCn-3PUFA) eicosapentaenoic acid (EPA, c20:5n-3) and docosahexaenoic acid (DHA, c22:6n-3) may protect against type 2 diabetes development. The aim of this current study is to determine whether LCn-3PUFA status is associated with type 2 diabetes in the Hunter Community Study.

View Article and Find Full Text PDF

Synopsis of recent research by authors named "Anu Alex"

  • - Anu Alex's research primarily focuses on the treatment of Meniere's disease, with studies comparing the efficacy of different intratympanic therapies such as gentamicin and methylprednisolone, catering to both patients with serviceable and non-serviceable hearing.
  • - The author has also explored rare medical presentations, including cases of skull base osteomyelitis and bacterially induced syndromes highlighting the complexities in diagnosing and managing these conditions.
  • - Additionally, Anu Alex has conducted systematic reviews on the effects of long-chain omega-3 polyunsaturated fatty acids on cognitive decline and their association with type 2 diabetes, indicating a broader interest in nutritional impacts on health.

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_session4o5e3p6627lqv06v8jrsu5nge01hftnb): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once