Publications by authors named "Antti E T Nissinen"
Clin Chem Lab Med
January 2008
Article Synopsis
- Alcohol is a leading cause of death linked to diseases in Western countries, highlighting the need for effective biomarkers to detect excessive use.
- Carbohydrate-deficient transferrin (CDT) and the combination of gamma-glutamyltransferase (GGT) with CDT are the most reliable current markers for monitoring alcohol intake.
- Emerging biomarkers like phosphatidylethanol and ethyl glucuronide show promise for better early detection of alcohol abuse but are not yet standard in clinical settings.
Pathophysiology
April 2004
Article Synopsis
- Moderate alcohol consumption can raise good HDL cholesterol levels and lower bad LDL cholesterol levels, potentially protecting against coronary heart disease.
- Alcohol affects proteins that manage lipoprotein metabolism, which are key to how the body processes cholesterol.
- The impact of ethanol on lipoproteins and their interaction with arterial wall cells is complex and requires more research to fully understand its role in atherosclerosis development.
