Background: the long-term effect of the use of drugs with anticholinergic activity on cognitive function remains unclear.
Methods: we conducted a systematic review and meta-analysis of the relationship between anticholinergic drugs and risk of dementia, mild cognitive impairment (MCI) and cognitive decline in the older population. We identified studies published between January 2002 and April 2018 with ≥12 weeks follow-up between strongly anticholinergic drug exposure and the study outcome measurement.
Aims: (i) To evaluate the effect of receiving one of two brief interventions in reducing alcohol consumption among general hospital patients compared with usual care. (ii) To assess whether a brief intervention of self-efficacy enhancement was superior to a self-help booklet in reducing alcohol consumption.
Design: A three-arm cluster randomized controlled trial.
Background: The uptake of influenza vaccination among older people is suboptimal. Contact with a doctor or nurse is associated with older people deciding to accept influenza vaccination.
Aim: To compare different forms of approach in improving uptake of influenza vaccination among patients aged 75 years and over in primary care.
Background: There is a lack of evidence on the most effective primary care management of older people with minor depression.
Aim: To evaluate a follow-up assessment by the community mental health team (CMHT) for older people with depressive symptoms identified by practice nurses at a health check for people over the age of 75 years.
Design Of Study: A pragmatic randomised controlled trial.