Synopsis of recent research by authors named "Antony Basten"
- Antony Basten's research primarily focuses on the mechanisms of B cell differentiation and the role of germinal centers in humoral immunity, highlighting the processes by which memory B cells and plasma cells are generated and the impact of high-affinity antigens.
- Recent findings from his work revealed the genetic and structural basis of the human anti-α-galactosyl antibody response, elucidating adaptive immune responses and potential implications for anaphylaxis and autoimmune conditions.
- Basten also explored the complexities of self-tolerance in B cells, providing insights into autoimmune diseases and the factors influencing the survival and differentiation of self-reactive germinal center B cells, thus contributing to the broader understanding of immune regulation.
