[Global study on tobacco use among youth 13-15 years old in the Russian Federation: dynamic surveillance 2004-2021].

Unlabelled: The article is devoted to the analysis of the results of the global surveys among youth 13-15 years old on tobacco consumption, conducted in 2004, 2015, 2021 in Khabarovsk, Novosibirsk, Cheboksary, Moscow, Pskov and the Russian Federation. The dynamics and trends in consumption of tobacco, electronic nicotine delivery systems (ENDS) and heated tobacco products (HTPs) are analyzed.

Materials And Methods: The surveys used representative samples formed on the basis of all public schools.

Time-of-flight mass spectrometer for diagnostics of continuous plasma flow.

This paper describes a version of the time-of-flight mass spectrometer based on a modified two-field acceleration approach of Wiley and McLaren. The aim of the device is a diagnostic of continuous plasma flow. The acceleration scheme idea, the construction of the spectrometer, and results of testing in plasma flow of Gd and CeO generated by vacuum arc discharge are described.

Deprotonated diaminocarbene platinum complexes for thermoresponsive luminescent silicone materials: both catalysts and luminophores.

,-Chelate deprotonated diaminocarbene platinum(II) complexes were synthesized by coupling coordinated isocyanides and azinyl-substituted ureas. The complexes act as catalysts of α,ω-divinylpolydimethylsiloxane and poly(dimethylsiloxane--methylhydrosiloxane) hydrosilylation cross-linking. Silicone rubbers obtained with (aminoisoquinoline)-containing complex 3d exhibit temperature-responsive luminescence.

Effects of turbulent environment and random noise on self-organized critical behavior: Universality versus nonuniversality.

Self-organized criticality in the Hwa-Kardar model of a "running sandpile" [Phys. Rev. Lett.

Successful use of topical minoxidil in the treatment of hypotrichosis associated with desmoplakin mutations.

Syndromes associated with desmosomal protein mutations such as desmoplakin can result in hair abnormalities including congenital alopecia and hypotrichosis. Herein, we present an 8-year-old boy, with a combination of two heterozygous mutations in the DSP gene encoding desmoplakin associated with congenital alopecia and long-standing hypotrichosis, who was treated with off-label use of topical minoxidil 5% foam once daily with dramatic growth after 2 months of therapy and sustained results at 1 year. Topical minoxidil may be effective in management of congenital alopecia and hypotrichosis associated with desmoplakin mutations.

Bullous Pemphigoid Associated With a New Combination Checkpoint Inhibitor Immunotherapy.

Novel immunotherapies including antibodies to programmed death ligand 1 (PD-1) and cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) have become common therapies for neoplasms including metastatic melanoma and non-small cell lung cancer (NSCLC). Dermatologic toxicity is the most common adverse event associated with these immunotherapies. We report a case of bullous pemphogoid (BP) in a patient receiving combination durvalumab and tremelimumab, two newer immunotherapy checkpoint inhibitors under investigation in phase III trials.

Phylloid terminal hair nevus: A unique clinical entity.

We present a case of an otherwise healthy infant with a localized patch of phylloid hypopigmentation bordered by terminal hairs on the back. We believe that this is a unique clinical entity and propose the term "phylloid terminal hair nevus." We believe that this is a localized form of phylloid hypomelanosis that is not associated with extracutaneous abnormalities.

Statistical symmetry restoration in fully developed turbulence: Renormalization group analysis of two models.

In this paper we consider the model of incompressible fluid described by the stochastic Navier-Stokes equation with finite correlation time of a random force. Inertial-range asymptotic behavior of fully developed turbulence is studied by means of the field theoretic renormalization group within the one-loop approximation. It is corroborated that regardless of the values of model parameters and initial data the inertial-range behavior of the model is described by the limiting case of vanishing correlation time.

A review of bullous pemphigoid associated with PD-1 and PD-L1 inhibitors.

Background: Dermatologic toxicity represents a substantial portion of all immune-related adverse events (irAEs) associated with PD-1/PD-L1 inhibitors. Bullous pemphigoid (BP) is a rare cutaneous side effect of these medications, which can initially be clinically indistinguishable from other, low-grade cutaneous toxicity.

Objective: To better characterize the clinical features of BP associated with PD-1/PD-L1 inhibitors, evaluate the efficacy of various treatment regimens, determine the frequency of prodromal pruritus, and assess whether immunological diagnostic studies for BP are warranted in patients treated with checkpoint inhibitors who develop intractable pruritus.

Survival of Mesenchymal Stem Cells in Different Methods of Nebulization.

We compared survival of bone marrow mesenchymal stem cells after compressor, ultrasound, and mesh nebulization of the cell suspension over 10 min. Viability of stromal cells was best preserved after compressor nebulization (72%). Cell survival after ultrasonic nebulization was significantly lower (20%).

Assessment of Infantile Hemangiomas Using a Handheld Wireless Diffuse Optical Spectroscopic Device.

Background/objectives: Infantile hemangiomas (IHs) are vascular tumors with the potential for significant morbidity. There is a lack of validated objective tools to assess IH severity and response to treatment. Diffuse optical spectroscopy (DOS), a noninvasive, nonionizing imaging modality, can measure total hemoglobin concentration and hemoglobin oxygen saturation in tissue to assess IH vascularity and response to treatment.

Turbulent compressible fluid: Renormalization group analysis, scaling regimes, and anomalous scaling of advected scalar fields.

We study a model of fully developed turbulence of a compressible fluid, based on the stochastic Navier-Stokes equation, by means of the field-theoretic renormalization group. In this approach, scaling properties are related to the fixed points of the renormalization group equations. Previous analysis of this model near the real-world space dimension 3 identified a scaling regime [N.

Feed and Wrap MRI Technique in Infants.

The feed and wrap technique refers to the use of feeding and swaddling to induce natural sleep in infants. It can be used prior to an magnetic resonance imaging (MRI) scan, avoiding sedation or anesthesia. We performed a retrospective review of feed and wrap MRI scans in infants 3 months or younger over a 2-year period at our center (279 scans) to evaluate the efficacy of this technique.

Malignant Melanoma With Rhabdomyosarcomatous Differentiation: A Case Report.

Malignant melanoma may exhibit morphologic characteristics of nonmelanocytic cell or tissue components, a phenomenon termed divergent differentiation. Melanoma with rhabdomyosarcomatous differentiation is rare, with 6 definite cases in adults reported in the literature. The authors describe a 75-year-old man with a cutaneous lesion of the right ear initially diagnosed as malignant melanoma.

Directed percolation process in the presence of velocity fluctuations: Effect of compressibility and finite correlation time.

The direct bond percolation process (Gribov process) is studied in the presence of random velocity fluctuations generated by the Gaussian self-similar ensemble with finite correlation time. We employ the renormalization group in order to analyze a combined effect of the compressibility and finite correlation time on the long-time behavior of the phase transition between an active and an absorbing state. The renormalization procedure is performed to the one-loop order.

Anomalous scaling in magnetohydrodynamic turbulence: Effects of anisotropy and compressibility in the kinematic approximation.

The field-theoretic renormalization group and the operator product expansion are applied to the model of passive vector (magnetic) field advected by a random turbulent velocity field. The latter is governed by the Navier-Stokes equation for compressible fluid, subject to external random force with the covariance ∝ δ(t-t')k(4-d-y), where d is the dimension of space and y is an arbitrary exponent. From physics viewpoints, the model describes magnetohydrodynamic turbulence in the so-called kinematic approximation, where the effects of the magnetic field on the dynamics of the fluid are neglected.