Adenosine Deaminase as a Useful Biomarker for Diagnosis and Monitoring of Inflammatory Bowel Disease.

Background: Inflammatory bowel disease (IBD) is a multifactorial immunologically mediated disorder characterized by repeated cycles of exacerbations and remissions. Diagnosis and monitoring of ulcerative colitis (UC) and Crohn's disease (CD) as common types of IBD require the usage of unpleasant invasive methods such as colonoscopy and cross-sectional imaging. Development of a non-invasive biomarker panel including different inflammatory parameters for evaluation of various aspects of gut inflammation and disease course is a priority task.