Publications by authors named "Antonios Lysandrou"

Introduction: Wearable Activity Trackers (WATs) offer real-time feedback on activity levels. We assessed the impact of WAT usage on physicians' exercise habits.

Methods: Physicians from the Athens Medical Association, Greece (n = 742) responded to a self-administered questionnaire evaluating usage of WAT, demographic characteristics, specialty, and physical exercise habits.

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Although evidence indicates the association of lipoprotein(a) [Lp(a)] with atherosclerosis, the link with calcific aortic valve disease (CAVD) is unclear. This systematic review and meta-analysis explores the connection between Lp(a) and aortic valve calcification and stenosis (AVS). We included all relevant studies, indexed in eight databases, up to February 2023.

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Lipoprotein(a) (Lp(a)) is a low-density lipoprotein (LDL) cholesterol-like particle bound to apolipoprotein(a). Increased Lp(a) levels are an independent, heritable causal risk factor for atherosclerotic cardiovascular disease (ASCVD) as they are largely determined by variations in the Lp(a) gene (LPA) locus encoding apo(a). Lp(a) is the preferential lipoprotein carrier for oxidized phospholipids (OxPL), and its role adversely affects vascular inflammation, atherosclerotic lesions, endothelial function and thrombogenicity, which pathophysiologically leads to cardiovascular (CV) events.

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Article Synopsis
  • Significant improvements in treating coronary artery disease (CAD) have been made, emphasizing the importance of accurate diagnosis and management based on ischemia and viability evaluations.
  • Non-invasive imaging techniques like stress echocardiography, CT coronary angiography, and cardiac MRI have enhanced the assessment of CAD, including the evaluation of plaque morphology.
  • Advances in technologies like positron emission tomography (PET) and improved software for cardiac CT offer further insights, making it crucial to understand the strengths and limitations of each imaging method for effective treatment decisions.
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