Publications by authors named "Antonio de Jesus Lugo-Dimas"
Clin Appl Thromb Hemost
July 2019
Article Synopsis
- The MTHFR enzyme influences homocysteine levels, and genetic variants (polymorphisms) in its gene can alter its activity, potentially increasing the risk for thromboembolic diseases.
- A study examined how the C677T and A1298C polymorphisms in the MTHFR gene relate to homocysteine levels and prothrombotic markers in patients with pulmonary embolism (PE) and acute myocardial ischemia (AMI).
- Analyzing 334 patient records revealed that specific genotypes were significantly more common in those with thrombotic conditions, with elevated homocysteine levels associated with certain genetic alleles linked to increased risk of AMI and severe PE events.
