Fungal microbiota dynamics and its geographic, age and gender variability in patients with cystic fibrosis.

Objectives: In cystic fibrosis (CF), there is a predisposition to bronchial colonization by potentially pathogenic microorganisms, such as fungi. Our aims were to describe the dynamics of respiratory mycobiota in patients with CF and to evaluate the geographic, age and gender variability in its distribution.

Methods: Cohort study in which 45 patients with CF from four hospitals in three Spanish cities were followed up during a 1-year period, obtaining spontaneous sputum samples every 3 to 6 months.

Respiratory outcomes of "new" bronchopulmonary dysplasia in adolescents: A multicenter study.

Objective: Long-term respiratory consequences of bronchopulmonary dysplasia (BPD) in preterm infants born in the post-surfactant era ("new" BPD) remain partially unknown. The present study aimed to evaluate the respiratory outcomes of "new" BPD in adolescents who were born preterm.

Methods: This multicenter, cross-sectional study included 286 adolescents born between 2003 and 2005 (mean age: 14.

Comorbidities and course of lung function in patients with congenital esophageal atresia.

Objective: To describe the epidemiological characteristics, hospital follow-up, and course of patients who underwent surgery for esophageal atresia and its consequences on lung function.

Population And Methods: Retrospective, longitudinal, and analytical study. The medical records of patients with esophageal atresia born between 1996 and 2017 were reviewed.

Right ventricular dysfunction in adolescents with mild cystic fibrosis.

Background: In cystic fibrosis (CF) patients the right ventricle (RV) suffers a progressive deterioration, but it is not clear when these changes begin. The aim of this study was to analyze the RV function in CF patients with mild respiratory disease.

Methods: Color-Doppler-Echocardiographic studies were prospectively performed in CF adolescent patients and an age-matched control group.

[Inhaled antibiotic therapy in cystic fibrosis].

Cystic fibrosis is the most frequent fatal genetically-transmitted disease among Caucasians. Chronic bronchial infection, especially by Pseudomonas aeruginosa, is the main cause of morbidity and mortality in this disease. Aerosolized antibiotic therapy achieves high drug concentrations in the airway with low toxicity, allowing chronic use.