Serum tumor markers in pediatric osteosarcoma: a summary review.

Osteosarcoma is the most common primary high-grade bone tumor in both adolescents and children. Early tumor detection is key to ensuring effective treatment. Serum marker discovery and validation for pediatric osteosarcoma has accelerated in recent years, coincident with an evolving understanding of molecules and their complex interactions, and the compelling need for improved pediatric osteosarcoma outcome measures in clinical trials.

[Sclerosing osteomyelitis of the femur and thrombocytosis. A case report].

We present the case of a 13 year-old boy who had chronic sclerosing osteomyelitis of the right femur in whom S. aureus was confirmed as the etiologic agent. Typical picture was apparent after one year period in which there were two hospital admissions.