Publications by authors named "Antonio Pio Orlando"

Background: The haemostatic matrix (FloSeal) is a topical agent that provides effective haemostasis in a range of surgical applications. We evaluated this sealant for intraoperative haemostatic effectiveness in an observational series of patients undergoing surgery for the resection of primary and metastatic liver tumours.

Methods: A haemostatic matrix was applied directly to areas of bleeding.

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Article Synopsis
  • ADI-SS PEG 20,000 mw is an enzyme that lowers extracellular arginine levels, which can lead to decreased tumor size and improved liver function in patients with chronic hepatitis C and inoperable liver cancer.
  • In a study involving HCC patients, this treatment significantly reduced HCV viral levels by up to 99% in certain patients and was linked to better liver function and lower plasma arginine and serum nitric oxide levels.
  • The research suggests that the reduction of arginine may help in inhibiting viral replication, though the exact mechanisms behind this effect are still unclear.
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