Publications by authors named "Antonio Perazzo"

Objectives: This laboratory study assessed the performance of a novel fluoride dentifrice containing micro-fibrillated cellulose (MFC) and entrapped silica.

Methods: Removal of extrinsic stains was assessed using the pellicle cleaning ratio (PCR) method, and radioactive dentin abrasivity (RDA) was measured, to calculate a cleaning efficiency index (CEI). Fluoride efficacy was evaluated using widely used remineralization and fluoride uptake methods.

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Dentifrice performance in the removal of dental plaque is influenced by the interactions of dentifrice components with tooth surfaces. This randomized controlled clinical study assessed the effectiveness and safety of a novel fluoride dentifrice formulation that included a micro-fibrillated cellulose network with entangled microcrystalline cellulose and silica particles (Protegera), and compared this to a positive control fluoride dentifrice (Crest Cavity Protection™). Whole mouth dental plaque levels in 82 healthy adults were measured after the first supervised use, and following a week of twice daily use at home.

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Sickle cell anemia (SCA) is a disease that affects red blood cells (RBCs). Healthy RBCs are highly deformable objects that under flow can penetrate blood capillaries smaller than their typical size. In SCA there is an impaired deformability of some cells, which are much stiffer and with a different shape than healthy cells, and thereby affect regular blood flow.

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Phospholipids are the main constituents of cell membranes and act as natural stabilizers of milk fat globules. Phospholipids are used in a wide range of applications, e.g.

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Article Synopsis
  • Polyelectrolytes (PEs) are charged polymers found in polar solvents, and their viscosity behavior in solutions is complex.
  • Classical theories predict specific relationships between viscosity and polymer concentration, but recent experiments show different scaling laws.
  • The study identifies four regimes based on the interaction between polymer and salt concentrations to explain these discrepancies and highlights the effects of salt on the viscosity of PEs.
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It is often necessary to extract a small amount of a suspension, such as blood, from a larger sample of the same material for the purposes of diagnostics, testing or imaging. A practical challenge is that the cells in blood sediment noticeably on the time scale of a few minutes, making a representative subsampling of the original sample challenging. Guided by experimental data, we develop a Kynch sedimentation model to discuss design considerations that ensure a representative subsampling of blood, from a container of constant cross-sectional area, for the entire range of physiologically relevant hematocrit over a specified time of interest.

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Article Synopsis
  • * The study investigates how the components of Vibrio cholerae biofilms, including polysaccharides, proteins, and cells, interact to create unique mechanical and surface properties that influence biofilm behavior in various environments.
  • * A new capillary peeling technology is developed based on these findings, providing a method for removing or transferring biofilms on different surfaces, with potential applications for addressing biofilm-related health and industrial issues.
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In hydraulic fracturing, water is injected at high pressure to crack shale formations. More sustainable techniques use aqueous foams as injection fluids to reduce the water use and wastewater treatment of conventional hydrofractures. However, the physical mechanism of foam fracturing remains poorly understood, and this lack of understanding extends to other applications of compressible foams such as fire-fighting, energy storage, and enhanced oil recovery.

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Interfacial tension is a key parameter affecting industrially relevant properties of emulsions, such as morphology and stability. Although several methods are available to measure interfacial tension, they are based on generation of droplets starting from separate emulsion components and cannot directly probe the interfacial tension of an emulsion as such. Here, a novel microfluidic tensiometry device to measure interfacial tension of a water-in-oil emulsion in situ as a function of surfactant concentration is presented.

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Emulsions are suspensions of droplets ubiquitous in oil recovery from underground reservoirs. Oil is typically trapped in geological porous media where emulsions are either formed in situ or injected to elicit oil mobilization and thus enhance the amount of oil recovered. Here, we briefly review basic concepts on geometrical and wetting features of porous media, including thin film stability and fluids penetration modes, which are more relevant for oil recovery and oil-contaminated aquifers.

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Emulsions made of oil, water and surfactants are widespread soft materials with complex structures depending on composition and temperature. Emulsion phase behavior at rest has been widely investigated but flow-induced effects, which are very relevant in many applications, can still be further explored towards improved emulsion microstructural design. In this work, we use low energy emulsification processing to create small-sized emulsions.

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Understanding jet formation from non-Newtonian fluids is important for improving the quality of various printing and dispensing techniques. Here, we use a laser-based nozzleless method to investigate impulsively formed jets of non-Newtonian fluids. Experiments with a time-resolved imaging setup demonstrate multiple regimes during jet formation that can result in zero, single, or multiple drops per laser pulse.

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Embedded three-dimensional (EMB3D) printing is an emerging technique that enables free-form fabrication of complex architectures. In this approach, a nozzle is translated omnidirectionally within a soft matrix that surrounds and supports the patterned material. To optimize print fidelity, we have investigated the effects of matrix viscoplasticity on the EMB3D printing process.

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The flow behavior of fiber suspensions has been studied extensively, especially in the limit of dilute concentrations and rigid fibers; at the other extreme, however, where the suspensions are concentrated and the fibers are highly flexible, much less is understood about the flow properties. We use a microfluidic method to produce uniform concentrated suspensions of high aspect ratio, flexible microfibers, and we demonstrate the shear thickening and gelling behavior of such microfiber suspensions, which, to the best of our knowledge, has not been reported previously. By rheological means, we show that flowing the suspension triggers the irreversible formation of topological entanglements of the fibers resulting in an entangled water-filled network.

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Although the phase behavior of emulsions has been thoroughly investigated, the effect of flow on emulsion morphology, which is relevant for many applications, is far from being fully elucidated. Here, we investigate an emulsion based on two common nonionic surfactants in a range of water concentration where complex and diverse microstructures are found at rest, such as multilamellar and bicontinuous phases. In spite of such complexity, once subjected to shear flow, all the emulsions investigated are characterized by thinning filaments which eventually break up into a concentrated suspension of micro-sized water-based droplets dispersed in a continuous oil phase.

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