Publications by authors named "Antonio Palma"

Introduction: The introduction of multiparametric prostate magnetic resonance imaging (mpMRI) has revolutionized prostate cancer (PCa) diagnosis, enhancing the localization of clinically significant prostate cancer (csPCa) and guiding targeted biopsies. However, significant disparities in the execution, interpretation, and reporting of prostate MRI examinations across centers necessitate greater standardization and accuracy. This study compares the diagnostic efficacy of mpMRI from academic and nonacademic centers in detecting csPCa and identifies factors associated with csPCa detection.

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  • The study investigates how cancer cells influence the fitness of surrounding tumor microenvironment (TME) cells through a mechanism involving a long non-coding RNA called Tu-Stroma, which alters the expression of Flower isoforms, impacting their growth advantage.
  • The expression of Flower Win isoforms in cancer cells enhances their dominance over TME cells that express Flower Lose isoforms, leading to reduced fitness in the TME.
  • Targeting Flower proteins with a humanized monoclonal antibody in mice has shown promising results, significantly reducing cancer growth and metastasis while improving survival rates and protecting organs from potential lesions.
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Introduction: While pedaling, cyclists rest their pelvis on the saddle, generating pressures on it. The pressures generated on the saddle are influenced by several factors. This study aimed to evaluate whether the flexibility of hamstring and lower back muscles could be considered a predictor of pressures in the anterior region (PAR) on the saddle.

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Practicing physical activities or sports that involve frequent jumping and landing can strain the muscles and joints of the lower limbs, especially in those who do not have adequate physical preparation. The objective of this study was to (a) determine the correlation between ankle range of motion (ROM) and landing stability following jumps; (b) assess the association between the jump height in a counter-movement jump (CMJ) test and ankle ROM; and (c) examine the connection between stabilometry during specific jumps movements present in many sports and in ankle stabilization. Sixty-two healthy amateur volleyball players participated in the study (age: thirty-seven females and twenty-five males; age (years): 16.

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  • Cancer involves complex cellular processes and gene expression, and advancements in techniques like single-cell sequencing and seqFISH have enabled precise mapping of cells based on gene expression.
  • The integration of machine learning and artificial intelligence with these datasets allows for comprehensive analysis of any tissue, offering insights into how cells communicate in the tumor microenvironment and identifying potential biomarkers for treatment.
  • This review focuses on pancreatic cancer, detailing how spatial transcriptomics and AI aid in understanding the disease and suggesting that combining these tools with other data can lead to earlier diagnoses and more personalized treatment approaches for patients.
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Background: The movement of the barbell has been detected as success factor for the snatch and the clean and jerk events. As the barbell's movement has been shown to be related to the athlete's body movement, we hypothesized that the latter could be a success factor also for the back squat (BS) event. Hence, this study aimed to investigate postural control during the execution of the BS at different load intensities in powerlifters and weightlifters.

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Introduction: Charcot-Marie-Tooth disease (CMT) is an inherited neuropathy that affects the sensory and motor nerves. It can be considered the most common neuromuscular disease, with a prevalence of 1/2500.

Methods: Considering the absence of a specific medical treatment and the benefits shown by physical activity in this population, a systematic review was completed using several search engines (Scopus, PubMed, and Web of Science) to analyze the use, effectiveness, and safety of a training program performed in telecoaching (TC).

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Background: Prismatic adaptation (PA) is a visuomotor technique using prismatic glasses that are capable of moving the visual field and to affect the excitability of certain brain areas. The aim of this pilot study was to explore potential acute effects of PA on penalty kick accuracy and postural control in youth soccer players.

Methods: In this randomized crossover study, seven young male soccer players performed three PA sessions (rightward PA, r-PA; leftward PA, l-PA; sham PA, s-PA) with a washout period of 1-week between them.

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  • Kidney stone disease (KSD) has become increasingly common, with a notable rise in incidence over the past decades, primarily affecting the renal system.
  • Most kidney stones are composed of calcium, particularly calcium oxalate, and often form on Randall's plaque, a calcium phosphate surface on kidney papillae.
  • To reduce the high recurrence rate of around 50% within five years, a better understanding of stone formation mechanisms is essential, along with targeted behavioral, nutritional, and pharmacological interventions.
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  • A study was conducted with 29 participants to examine the effects of static stretching (SS) and proprioceptive neuromuscular facilitation (PNF) on both local and non-local range of motion (ROM) over three sessions, including a control session.
  • Findings showed significant increases in local ROM for both dominant and non-dominant limbs after SS and PNF, but no differences were seen in non-local ROM measures like shoulder extension.
  • The results indicated that while both SS and PNF can effectively enhance local ROM, they do not appear to have significant effects on non-local ROM.
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  • The study explores the impact of COVID-19 lockdowns on nursery and primary school teachers, specifically their physical and mental health habits.
  • It involved 265 teachers who answered surveys about their physical activity levels, adherence to the Mediterranean Diet, and overall health perceptions.
  • Results showed primary school teachers had better physical activity levels and perceived health, with significant associations found between physical activity, weight status, and overall health outcomes.
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Background: The numerous restrictive measures implemented during the recent COVID-19 pandemic have reduced the levels of physical activity (PA) carried out by elderly people and telecoaching (TC) could be a training method to maintain the recommended levels of PA. In fact, TC uses information and digital communications technologies, such as computers and mobile devices, to access training services remotely. Thus, this study aimed to systematically review the scientific literature to verify the application, efficacy, and safety of TC training programs.

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Background: Quarantine was one of the strategies adopted by governments against the spread of COVID-19. This restriction has caused an increase in sedentary behaviors and a decrease in the practice of physical activity (PA), with a consequent negative impact on lifestyle both in healthy people and in those who need constant practice of PA to combat diseases, such as patients suffering from neuromuscular diseases (NMDs). Hence, this study aimed to compare PA levels among patients with NMD during and after quarantine.

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  • This study explored how internal load (IL) and external load (EL) are linked and their impact on predicting injury risk (IR) in male professional soccer players using machine learning (ML) techniques.
  • The research reviewed 25 studies, highlighting significant positive correlations between perceived exertion (S-RPE) and various EL measures, indicating a relationship between training load and injury risk.
  • The findings suggest that ML approaches can effectively predict IL and IR, and new indexes combining EL and IL can enhance understanding of training load and player fitness.
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  • Resistance training can really help cancer survivors stay healthy and strong.
  • It's shown to work well both during and after cancer treatment to keep or build muscle.
  • But most studies focus on adult survivors, so this work looks at if kids and teens with cancer should do the same type of training.
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Background: Few studies have investigated the effects of adopting a specific and prolonged posture on cyclists. This study aimed to evaluate the upright spine in a sample of recreational cyclists and compare it with a sample of non-cyclists, though still athletes, through a 3D scanning method.

Methods: Forty-eight participants were enrolled in this observational study.

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Cells have evolved their communication methods to sense their microenvironments and send biological signals. In addition to communication using ligands and receptors, cells use diverse channels including gap junctions to communicate with their immediate neighbors. Current approaches, however, cannot effectively capture the influence of various microenvironments.

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Over the past 50 years, socioeconomic development has brought a reduction in birth rates, an increase in life expectancy and consequently in the elderly population. For this reason, there has been an increasing focus on physical and mental health of the elderly, promoting the concept of healthy aging. The aim of this study was to explore the associations between perceived physical and mental health of older adults and a variety of determinants, such as demographic factors, physical functional fitness, physical activity level, adherence to the Mediterranean diet and anthropometric indices, through a structural equation modeling (SEM).

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Purpose: Low back pain is the most frequently reported musculoskeletal disorder and represents one of the highest patient burdens in healthcare. This systematic review and meta-analysis aimed to investigate the effectiveness of Pilates exercise on pain intensity and functional disability caused by low back pain (LBP).

Materials And Methods: A Systematic review with meta-analysis was conducted.

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Pillitteri, G, Clemente, FM, Petrucci, M, Rossi, A, Bellafiore, M, Bianco, A, Palma, A, and Battaglia, G. Toward a new conceptual approach to "intensity" in soccer player's monitoring: A narrative review. J Strength Cond Res 37(9): 1896-1911, 2023-In the last decade, monitoring physiological and match-related demands in soccer has become an increasingly common practice in sports sciences.

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Background: Manual dexterity is the ability to manipulate objects using the hands and fingers for a specific task. Although manual dexterity is widely investigated in the general and special population at all ages, numerous aspects still remain to be explored in children. The aim of this study was to assess the presence of the training effect of the execution of the Grooved Pegboard test (GPT) and to measure the performance of the GPT in dual-task (DT), i.

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Introduction: Wheelchair fencing (WF) is a very practiced sport within the Paralympic world. A careful analysis of the characteristics and data of a WF athlete can be useful for coaches and movement experts to better plan a training program. The objective of the study was to evaluate physical fitness assessment methods adopted in WF and to propose a standard operating procedures (SOP).

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The contact point of the pelvis with the saddle of the bicycle could generate abnormal pressure, which could lead to injuries to the perineum in cyclists. The aim of this review was to summarize in a narrative way the current literature on the saddle pressures and to present the factors that influence saddle pressures in order to prevent injury risk in road and off-road cyclists of both genders. We searched the PubMed database to identify English-language sources, using the following terms: "saddle pressures", "pressure mapping", "saddle design" AND "cycling".

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