Background: Junctional epidermolysis bullosa (JEB) is one of the four major types of EB caused by genetic variants in the genes coding the proteins of the lamina lucida. All patients with this major type of EB present syndromic hypoplastic amelogenesis imperfecta (AI), with either a pits and fissures or generalized hypoplastic phenotype. Severe forms of AI are associated with compromised oral health-related quality of life (QoL) mostly due to poor dental aesthetics, dentofacial anomalies, and oral pain.
View Article and Find Full Text PDFIntroduction: Epidermolysis bullosa (EB) is a rare genetic disorder characterized by skin fragility and blister formation. The phenotypic presentation is broad with four major types, being Recessive Dystrophic EB (RDEB) the most severe, including oral anomalies such as severe microstomia, ankyloglossia, vestibule obliteration and occlusal anomalies, turning orthodontic treatment into a challenge.
Aim: This case report aims to present the comprehensive treatment of a patient with severe RDEB, including periodontal surgery, orthodontic fixed braces with mini-screws and oral rehabilitation with anterior veneers.
J Mech Behav Biomed Mater
March 2021
Objective: The aim of this in vitro study was to analyze the failure of occlusal veneers made of three different restorative CAD/CAM materials under lateral static loading.
Materials And Methods: Sixty standardized semi-anatomical occlusal veneers were fabricated on natural lower molars from three different CAD/CAM materials: hybrid ceramic (Vita Enamic), lithium disilicate (IPS e. max CAD) and translucent zirconia (Bruxzir).