Publications by authors named "Antonio Melo-Gouveia"
Article Synopsis
- The study investigates how different Portuguese NHS hospitals adopt biosimilars compared to originator biologic drugs, focusing on factors influencing this uptake from 2015 to 2021.
- Analysis shows that academic hospitals adopted certain biosimilars faster, while higher overall biologic usage corresponded with lower biosimilar uptake.
- Improving awareness and training on biosimilar prescribing could lead to significant cost savings, potentially totaling 13.9 million euros annually if all hospitals matched the highest uptake rates.
The use of morphine applied topically to painful wounds has potential advantages, such as dose reduction, fewer side effects and compound formulations, have been proposed for this purpose. Given the potential high impact of drug product quality on a patient's health, the aim of the present study was to develop two stable sterile hydrogels containing morphine hydrochloride, intended for topical application on painful wounds. Two carboxymethylcellulose sodium-based hydrogels were prepared containing 0.
View Article and Find Full Text PDFBackground: Primary cutaneous lymphomas (extranodular non-Hodgkin lymphomas) are rare (incidence 1:100 000). Mycosis fungoides is the most common cutaneous T-cell lymphoma (CTCL) subtype. Treatment options are based on the diagnosis and the stage of the disease.
View Article and Find Full Text PDF