Publications by authors named "Antonio Marco Marzo"
Few data are available on the role of SBRT re-irradiation for isolated recurrences. We designed a prospective phase I study to evaluate the maximum tolerated dose (MTD) of SBRT for thoracic re-irradiation, for peripheral lung lesions. RT was delivered with a dose escalation design from 30 Gy in five fractions up to 50 Gy in five fractions.
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- A phase III randomized trial compared the effectiveness of linac-based stereotactic radiosurgery (SRS) to a multi-source gamma-ray system for treating brain metastases in adults with solid tumors.
- The primary focus was on the incidence of symptomatic radionecrosis, while secondary outcomes included local progression, distant brain failure, and overall survival.
- Results showed no significant difference in outcomes between the two methods, with both presenting similar rates of symptomatic radionecrosis and other complications despite variations in treatment times.
Background: The standard of care for elderly, newly-diagnosed glioblastoma patients consists, if feasible, of surgical resection followed by a short course of radiation therapy (RT) with concomitant and adjuvant temozolomide chemotherapy (TMZCHT). To date, the literature lacks of consistence in the definition of elderly, if older than 65 years, or 70 years. Aim of this study was to explore whether differences exist between these two cohorts, comparing outcomes using a propensity score matched analysis (PSM).
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