Publications by authors named "Antonio Ludgero-Correia"
Whole-genome analysis uncovers loss of blaZ associated with carriage isolates belonging to methicillin-resistant Staphylococcus aureus (MRSA) clone ST5-VI in Cape Verde.
J Glob Antimicrob Resist
September 2021
Article Synopsis
- Surveillance studies of Staphylococcus aureus in Cape Verde reveal high genetic diversity, with 27 different sequence types identified and significant genetic clusters.* -
- Analysis of 106 isolates showed notable genetic changes, including multiple instances of plasmid loss in MRSA strains, linked to resistance characteristics and adaptation trends.* -
- The findings emphasize the importance of genomic data for understanding MRSA evolution, which can inform the development of future infection control strategies.*
Objectives: Data on baseline drug resistance important in informing future antimicrobial stewardship programs. So far, no data on the antimicrobial drug resistance of clinical isolates available for the African archipelago of Cabo Verde.
Methods: We performed a retrospective analysis over years (2013-17) of the drug susceptibility profiles of clinical isolates in the two main hospitals of Cabo Verde.
Objective: The goal of this study was to investigate the combined effects of ovariectomy (OVX) and high-fat diet (HF) on insulin sensitivity and pancreatic remodeling in C57BL/6 mice treated with bezafibrate.
Methods: Female C57BL/6 mice were subjected to OVX or surgical procedure without removal of the ovary (SHAM). Animals received standard chow (SC; 10% lipids) or HF (60% lipids).
Objective: We hypothesized that a high-fat (HF) diet aggravates ovariectomy-related complications. To test this hypothesis, ovariectomized (OVX) mice were fed a HF diet, and we investigated the lipid metabolism, adipose tissue remodeling, adipokines, and inflammatory cytokines.
Methods: To investigate the situation in a mouse model of ovariectomy, OVX and SHAM C57BL/6 mice fed a HF diet (60% fat) or standard chow (SC, 10% fat) were monitored for 18 wk.