Publications by authors named "Antonio Leon"

Article Synopsis
  • The study is investigating the effectiveness of structured health interventions in preventing type 2 diabetes and cardiovascular disease specifically in low socioeconomic populations, as previous trials have shown mixed results in the general population.
  • The research will involve 3,000 participants aged 50-59 from 30 primary care centers in Stockholm, comparing systematic health dialogues to more casual opportunistic screenings.
  • Key outcomes include changes in systolic blood pressure, other biological risk factors, and lifestyle habits measured at 6 and 12 months, alongside long-term effects tracked through national registries.
View Article and Find Full Text PDF

Background: In Norrtälje municipality, within Region Stockholm, there is a joint integrated care organisation providing health and social care, which may have facilitated a more coordinated response to the covid-19 pandemic compared to the otherwise decentralised Swedish system. This study compares the risk of covid-19 mortality among persons 70 years and older, in the municipalities of Stockholm, Södertälje, and Norrtälje, while considering area and individual risk factors.

Methods: A population-based study using linked register data to examine covid-19 mortality among those 70 + years (N = 127,575) within the municipalities of interest between the periods March-August 2020 and September 2020-February 2021.

View Article and Find Full Text PDF

Background: The eruption of the Tajogaite volcano began on the island of La Palma on September 19, 2021, lasting for 85 days. This study aims to present the design and methodology of the ISVOLCAN (Health Impact on the Population of La Palma due to the Volcanic Eruption) cohort, as well as the preliminary findings from the first 1002 enrolled participants.

Methods: A prospective cohort study was conducted with random selection of adult participants from the general population, with an estimated sample size of 2600 individuals.

View Article and Find Full Text PDF

Evidence of inequality in the utilisation of mental health care (MHC) by adolescents in Nordic countries is mixed. This study aims to investigate if there are socioeconomic differences in the utilisation of MHC, while accounting for adolescents' mental health status. We analysed a cohort of 3517 adolescents, followed from 7 to 9th grade (ages 13-16), to examine the association between parental socioeconomic position (SEP: education and disposable income), adolescents' estimated needs, and the utilisation of MHC (defined as visits to secondary psychiatric care or receipt of psychotropic medication).

View Article and Find Full Text PDF

Background: The coronavirus disease 2019 (COVID-19) disproportionately affects minority populations in the USA. Sweden - like other Nordic countries - have less income and wealth inequality but lacks data on the socioeconomic impact on the risk of adverse outcomes due to COVID-19.

Methods: This population-wide study from March 2020 to March 2022 included all adults in Stockholm, except those in nursing homes or receiving in-home care.

View Article and Find Full Text PDF

Serum resistin is a pro-inflammatory cytokine that has been described as a risk factor associated with mortality in several clinical sets including type 2 diabetes. Mortality studies in the general population are needed to find out the risk of death associated to this cytokine. In a follow-up study of a cohort of adult population (n = 6636) in Spain over a period of fifteen years (447 deaths/102,255 person-years), serum resistin measurements and death records were obtained.

View Article and Find Full Text PDF

Background: There is a need for evidence that residency training in family medicine can benefit the care of patients in primary care in low- and middle-income countries. We tested the hypothesis that two years of residency training in family medicine enables doctors to better detect chronic health conditions while requesting fewer laboratory tests and providing more follow-up visits.

Methods: We performed a retrospective longitudinal observational analysis of medical consultations from 2013 to 2018 in primary care in Rio de Janeiro, comparing doctors without residency training in family medicine (Generalists) versus family physicians (FPs).

View Article and Find Full Text PDF

Prostatic carcinoma withsignet ring cells is a very rare histopathological entity, withfew infected cases in the literature, for which there is nomanagement protocol.  DESCRIPTION OF CASES: Two patients are presented,one 46 years old and the other 76 years old, the firstdebuts with a decompensated picture of urinary and intestinalobstruction, and the second presents a torpid evolutionof his disease with progression from stage I to III in threemonths.  DISCUSSION: Mucosacretory prostate tumors have theirown morphohistological and immunohistochemical characteristics,which differentiate them from classic adenocarcinomas.

View Article and Find Full Text PDF

Introduction: Grading dysphagia is crucial for clinical management of patients. The Eckardt score (ES) is the most commonly used for this purpose. We aimed to compare the ES with the recently developed Brief Esophageal Dysphagia Questionnaire (BEDQ) in terms of their correlation and discriminative capacity for clinical and manometric findings and evaluate the effect of gastroesophageal reflux symptoms on both.

View Article and Find Full Text PDF

Introduction: Reducing avoidable hospital admissions is often viewed as a possible positive consequence of introducing integrated care (IC). The aim of this study was to investigate the impact of implementing IC in Norrtälje on the rate of admissions for ambulatory care sensitive conditions (ACSC).

Method: Using interrupted time series analyses we investigated the effect of implementing IC in Norrtälje municipality in the northern part of Stockholm county, Sweden.

View Article and Find Full Text PDF

OBJECTIVE To estimate the seroprevalence of antibodies to SARS-CoV-2 among blood donors in the state of Rio de Janeiro, Brazil. METHODS Data were collected on 2,857 blood donors from April 14 to 27, 2020. This study reports crude prevalence of antibodies to SARS-CoV-2, population weighted prevalence for the state, and prevalence adjusted for test sensitivity and specificity.

View Article and Find Full Text PDF

The relationship between fructose intake and insulin resistance remains controversial. Our purpose was to determine whether a reduction in dietary fructose is effective in decreasing insulin resistance (HOMA2-IR). This field trial was conducted on 438 adults with overweight and obese status, without diabetes.

View Article and Find Full Text PDF

Objective: This study aims to describe the presence of bladder foreign body as a rare complication following intraprostatic ethanol injection.

Case Reports:  A 71-year-old man and a 70-year-old male with bladder catheter probe due to obstructive benign prostatic enlargement underwent ethanol injection via transrectal echography.

Results: The first patient presented a urinary infection with acute urinary retention one year after the procedure.

View Article and Find Full Text PDF

The impact of air pollution on hospitalizations for total respiratory diseases (DRT) among children under five (DRC), as well as for cardiovascular diseases (CVD) in patients over 39 years of age, was examined in the municipalities of Belo Horizonte, Betim and Contagem, of the Metropolitan Region of Belo Horizonte, Minas Gerais. Generalized additive models using Poisson regression were used to adjust the daily time series of hospitalizations. Single and accumulated lagged pollutants of up to five days were introduced as independent variables and models were adjusted for temperature, humidity, weekdays and holidays.

View Article and Find Full Text PDF

Unlabelled: Prostate cancer (PCa) is one of the most frequent neoplasms in the masculine sex, which has multiple etiological factors, inflammation is one of them.

Objective: To determine the role of different inflammatory markers in the diagnosis of PCa in first prostatic biopsies.

Methods: This is a prospective study evaluating neutrophil/ lymphocyte (NLR), neutrophil/monocyte (NMR) and platelet/lymphocyte (PLR) ratios of 78 patients with suspected PCa due to PSA alteration and/or abnormal digital rectal examination, and its correlation with twelve-cylinder biopsy result.

View Article and Find Full Text PDF

Indoor air pollution is exacerbated by the burning of firewood in rustic stoves and poorly ventilated environments. Exposure to the pollutants emitted by this type of fuel results in increased morbidity and mortality. In Brazil, studies and estimates regarding these conditions are scarce.

View Article and Find Full Text PDF

Objectives: Partial nephrectomy was historically used in urology for the treatment of benign kidney processes. In the last 20 years, its greater use was focused on localized tumors being an alternative to radical nephrectomy. Initially, absolute indications included patients with a single kidney or bilateral tumors.

View Article and Find Full Text PDF

Mental health problems during adolescence constitute a major public health concern today for both families and stakeholders. Accordingly, different family-based interventions have emerged as an effective treatment for adolescents with certain disorders. Specifically, there is evidence of the effectiveness of concrete approaches of systemic family therapy on the symptoms of adolescents and family functioning in general.

View Article and Find Full Text PDF

Background: The continuous growth of the current dementia epidemic is contingent on the stability of age- and sex-specific trends over time. However, recent evidence suggests declining or stable trends. The aim of this study was to evaluate the real-world changes in the burden of dementia in older adults in Sweden from 1987 to 2016 by estimating age- and sex-specific incidence of dementia diagnosis in hospital inpatient records (dementia incidence).

View Article and Find Full Text PDF

Objective: To determine the incidence and clinical and histopathological characteristics of patients with prostatic evanescent carcinoma in the Urology Department of the Hospital Universitario de Caracas.

Methods: We reviewed the medical records of 257 patients undergoing radical prostatectomy for a previous diagnosis of prostatic carcinoma in the period January 2010 to June 2016.

Results: Four patients had evanescent carcinoma corresponding to 1.

View Article and Find Full Text PDF

Myokines are peptides produced and released by myocytes of muscle fibers that influence physiology of muscle and other organs and tissues. They are involved in mediating the beneficial effects that exercise has on health. More than one hundred have been identified and among them are IL6, myostatin, irisin, mionectin and decorin.

View Article and Find Full Text PDF

Background: Currently available treatments for secondary progressive multiple sclerosis(SPMS) have limited efficacy and/or safety concerns. Adipose-mesenchymal derived stem cells(AdMSCs) represent a promising option and can be readily obtained using minimally invasive procedures.

Patients And Methods: In this triple-blind, placebo-controlled study, cell samples were obtained from consenting patients by lipectomy and subsequently expanded.

View Article and Find Full Text PDF

Introduction: There is no information about the evolution of robotic programs in public hospitals of Latin-America.

Objective: To describe the current status and functioning of robotic programs in Latin-American public hospitals since their beginning to date.

Methods: We conducted a survey among leading urologists working at public hospitals of Latin-America who had acquired the Da Vinci laparoscopic-assisted robotic system.

View Article and Find Full Text PDF

Objective: Achieving residents' medical training of quality is a constant concern in the Confederación Americana de Urología (CAU), the third Urological Society worldwide. We aim to analyze the diversity of state training programs, with the intention to identify opportunities for global improvement within them and also to analyse the professional reality in different countries.

Methods: Data from 2nd and 3rd Foro Educativo CAU regarding postgraduate training and labour implications are reviewed.

View Article and Find Full Text PDF

Objective: To evaluate the impact of air pollution on hospitalizations for respiratory and cardiovascular diseases in the largest Brazilian metropolis.

Methods: This study was carried out at the Metropolitan Region of São Paulo, Brazil. Environmental data were obtained from the network of monitoring stations of nine municipalities.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionhjpds86k5506npq1dur5fmo1ltnspubm): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once