Publications by authors named "Antonio Jose Ledo A Cunha"
Objective: To describe the clinical characteristics of children and adolescents admitted to intensive care with confirmed COVID-19.
Method: Prospective, multicenter, observational study, in 19 pediatric intensive care units. Patients aged 1 month to 19 years admitted consecutively (March-May 2020) were included.
Background/objective: As a developing country, Brazil presents a wide range of environmental risks that can constitute hazards to child health. The country also presents different socio-economic-cultural conditions that could be responsible for determining different vulnerability and susceptibility levels for the population, which can potentiate the effects of the environmental pollutants. The Rio Birth Cohort Study (PIPA project) is a prospective maternal-infant health study, hosted in the city of Rio de Janeiro (Southeastern Brazil), designed to investigate separate and combined effects of environmental chemical pollutants, as well as the interactions between these exposures and sociocultural environment and epigenetic patterns.
View Article and Find Full Text PDFArticle Synopsis
- Leprosy remains prevalent in some developing countries, like India and Brazil, caused by the bacterium Mycobacterium leprae, leading to significant health complications.
- Although sensory loss is a major symptom, chronic pain associated with leprosy is now being acknowledged as a serious late complication.
- The article explores methods to assess leprosy-related pain and suggests potential factors contributing to its persistence, as well as new treatment avenues for chronic pain management in affected individuals.
Article Synopsis
- Surgical nerve decompression in leprosy aims to prevent nerve damage and enhance patients' quality of life (QoL) and sensory motor function.
- A study analyzed the QoL of 33 leprosy patients who had undergone neurolysis, focusing on their demographic and clinical information along with QoL scores.
- Results indicated an overall QoL mean of 11.2, with particular domain scores showing the highest satisfaction in social relations, suggesting the importance of incorporating QoL measures in patient rehabilitation assessments.
Objective: To describe the case-fatality rate (CFR) and risk factors of death in children with community-acquired acute pneumonia (CAP) in a pediatric university hospital.
Method: A longitudinal study was developed with prospective data collected from 1996 to 2011. Patients aged 1 month to 12 years were included in the study.
The objective of this study was to evaluate people attending a primary health clinic in Rio de Janeiro, Brazil for immunoreactivity to five Mycobacterium tuberculosis antigens, as these antigens are markers of immune response and factors associated with active TB. The serum antibody titers of different categories of patients (defined by microbiological and radiological characteristics and by response to therapy on follow-up) to 38 kDa, 16 kDa, MPT64, ESAT-6 and MT10.3 antigens were determined blind with ELISA.
View Article and Find Full Text PDFTuberculin skin test conversion among medical students at a teaching hospital in Rio de Janeiro, Brazil.
Infect Control Hosp Epidemiol
October 2002
Objective: To describe the cumulative incidence of and risk factors for tuberculosis (TB) infection among medical students.
Design: In 1999, a cohort study of medical students with negative results (induration < 10 mm) on tuberculin skin test (TST) was performed. Students who had undergone two-step testing in 1998 were retested.