Opinion article offering an up-to-date view and evolutionary prediction of the tremendous impact of the gradual but real permeation of the Basic Sciences into the field of Urology. The significance of the transition from anatomy/knowledge/surgical-technique to pathophysiological knowledge/basic-science/medical therapy is emphasised. These criteria provide food for thought in many areas of urology including vesico-prostatic function, erectile dysfunction and, more comprehensively, uro-oncology.
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