Publications by authors named "Antonio Carlos P Barretto"

Background: Blunted reflex muscle vasodilatory response during exercise in heart failure (HF) patients may be secondary to augmented vasoconstriction. We tested the hypothesis that the exaggerated sympathetic nerve activity restrains the reflex muscle vasodilatation during exercise in HF patients.

Methods: We studied the reflex vasodilatory response (plethysmography) during 3 min static handgrip exercise at 30% maximal voluntary contraction in 10 advanced HF patients (45 +/- 3 year, NYHA Functional Class III/IV) and 10 age-matched normal controls (NC, 40 +/- 3 year, P = 0.

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Article Synopsis
  • The study aimed to determine if exercise training can lower sympathetic neural activation at rest in patients with chronic advanced heart failure.
  • Sixteen heart failure patients were split into exercise-trained and sedentary groups, participating in a four-month program with monitored exercise sessions.
  • Results showed that exercise significantly reduced muscle sympathetic nerve activity in heart failure patients, making their levels comparable to those of healthy trained individuals, while also improving peak VO2 and forearm blood flow.
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Objectives: We sought to study: 1) the impact of hemodynamic and left ventricular function on short-term postexercise blood pressure reduction in elderly hypertensive patients; and 2) the 22-h postexercise effects on ambulatory blood pressure in elderly hypertensive patients.

Background: Although early exercise provokes postexercise blood pressure reduction, the mechanisms underlying this response are not completely understood. Besides, it is unclear whether the reduction in blood pressure after exercise lasts long enough to have clinical relevance in elderly hypertensive patients.

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