Publications by authors named "Antonio Carlos Moraes"
This study aimed to investigate recovery markers among elite climbers following the National Boulder Championship. We assessed maximum isometric hand grip strength (HS), forearm swelling (circumference), delayed soreness in forearm muscles, tiredness, and exercise readiness at several time points: pre-competition, immediately post-competition (within 4 min after their last effort), and 12, 24, 48, and 60 h post-competition. Maximum isometric hand grip strength decreased by 6.
View Article and Find Full Text PDFThis prospective, observational, open-label study aimed to provide access to ustekinumab prior to market authorization and assess its safety and effectiveness in patients with Crohn's disease (CD) refractory to anti-tumor necrosis factor-α and conventional drugs in Brazil. Patients with a diagnosis of moderate-to-severe active CD for ≥3 months before screening received ustekinumab in a single intravenous induction dose (~6 mg/kg) at week 0, and a 90 mg maintenance dose, subcutaneously, every 8 or 12 weeks, from week 8 through to 80. Serious adverse events (SAE), adverse drug reactions (ADR), clinical response (per CD Activity Index and Harvey Bradshaw Index (HBI) scores), remission (per HBI scores), biomarkers (C-reactive protein (CRP) and fecal calprotectin (FC)) and endoscopic improvement rate over 80 weeks were assessed.
View Article and Find Full Text PDFAnti-TNF therapy for ulcerative colitis in Brazil: a comparative real-world national retrospective multicentric study from the Brazilian study group of IBD (GEDIIB).
BMC Gastroenterol
May 2022
Article Synopsis
- Anti-TNF therapy has proven effective in treating ulcerative colitis (UC), but there's limited data on its impact on Brazilian patients; this study compares the efficacy of adalimumab (ADA) and infliximab (IFX) in achieving clinical and endoscopic remission after one year of treatment.
- Conducted across 24 centers, the study included 393 UC patients and utilized various statistical methods to analyze treatment outcomes, finding that IFX showed better clinical remission rates compared to ADA at 26 and 52 weeks.
- Results indicated a clinical remission rate of 82.82% at week 52, with IFX patients experiencing fewer instances of loss of response, although endoscopic remission rates did not significantly differ between the
The Relative Age Effect on Anthropometry, Body Composition, Biological Maturation and Motor Performance in Young Brazilian Soccer Players.
J Hum Kinet
January 2021
The present study aimed to investigate the influence of months of birth on anthropometry, body composition, biological maturation, and motor performance in young Brazilian soccer players. Young Brazilian soccer players from the Under-13 (n = 50; 13.6 ± 0.
View Article and Find Full Text PDFArticle Synopsis
- Inflammatory bowel diseases (IBD) are increasingly common chronic conditions in Brazil that significantly affect patients' health and quality of life over time.
- A study surveyed 286 physicians, primarily gastroenterologists and colorectal surgeons, about their experiences and challenges in treating IBD in various Brazilian regions.
- Key findings indicated difficulties in accessing medications and performing specialized procedures, with the most prescribed treatments being biological medications like infliximab and adalimumab, while discussions about therapy failures and new treatments were highlighted as priorities for healthcare conferences.
This study analyzed the physiological adjustments caused by the use of the Elevation training mask® (2.0), an airflow restriction mask (ARM) during continuous exercise. Eighteen physically active participants (12 men and 6 women) were randomized to two protocols: continuous exercise with mask (CE-ARM) and continuous exercise without mask (CE).
View Article and Find Full Text PDFThe objective of the study was to investigate the effects of using lifting straps on the lat pull-down exercise on maximal strength, number of repetitions, and muscle activation. Twelve resistance-trained men participated (age 27 ± 4 years, body mass 84 ± 10 kg, height 177 ± 6 cm, resistance training experience 6.6 ± 2.
View Article and Find Full Text PDFBackground: Adalimumab is a monoclonal antibody, tumor necrosis factor-alpha (TNFα) inhibitor that has efficacy for inducing and maintaining remission in moderate-to-severe ulcerative colitis. Real world studies with adalimumab in Latin American ulcerative colitis patients are scarce.
Objective: To assess the clinical remission rates in induction and maintenance with adalimumab therapy in ulcerative colitis.
Purpose: To investigate the effects of caffeine on performance, neuromuscular fatigue and perception of effort during high-intensity cycling exercise in moderate hypoxia.
Methods: Seven adult male participants firstly underwent an incremental exercise test on a cycle ergometer in conditions of acute normobaric hypoxia (fraction inspired oxygen = 0.15) to establish peak power output (PPO).