Degree of Agreement between Cardiovascular Risk Stratification Tools.

Background:: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in Brazil, and primary prevention care may be guided by risk stratification tools. The Framingham (FRS) and QRISK-2 (QRS) risk scores estimate 10-year overall cardiovascular risk in asymptomatic individuals, but the instrument of choice may lead to different therapeutic strategies.

Objective:: To evaluate the degree of agreement between FRS and QRS in 10-year overall cardiovascular risk stratification in disease-free individuals.

Economic evaluation of antipsychotic drugs for schizophrenia treatment within the Brazilian Healthcare System.

Objective: To assess the cost-utility of first and second-generation antipsychotics for treatment of schizophrenia.

Methods: A five-year Markov model was constructed based on a survey of the records of patients seen in 2006 at a psychosocial care center in the municipality of Florianopolis, Southern Brazil. Costs were evaluated from the perspective of the Sistema Unico de Saúde (SUS - Unified Healthcare System).