Role of (18)F-FDG PET/CT, (123)I-MIBG SPECT, and CT in Restaging Patients Affected by Malignant Pheochromocytoma.

Purpose: Pheochromocytoma (PH) is a rare catecholamine-secreting tumor that arises from chromaffin tissue within the adrenal medulla and extra-adrenal sites; commonly it is sporadic, and malignant PH accounts for about 10% of all cases. Several imaging modalities have been used for the diagnosis and staging of this tumor: functional imaging using radio-labelled metaiodobenzylguanidine and, more recently, (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG PET/CT), which offers substantial sensitivity and specificity to correctly detect metastatic PH and helps to identify patients suitable for treatment with radiopharmaceuticals. The aim of our study was to compare CT, (18)F-FDG PET/CT, and (123)I-metaiodobenzylguanidine single photon emission tomography ((123)I-MIBG SPECT) as feasible methods to restage patients diagnosed histologically with PH.

A clinical picture of chronic polyarticular tophaceous gout.

An unusual picture of polyarticular tophaceous gout is reported. It concerns a 61-year-old patient with tophaceous deposits for 30 years. Descriptive clinical and radiographic images are furnished.