Publications by authors named "Antonio Caetano"

Introduction: Diabetes, obesity, and CKD collectively impact musculoskeletal health and increase the risk of severe coronavirus disease 2019 (COVID-19) outcomes.

Methods: This cross-sectional study included 32 dialysis patients, categorized based on their COVID-19 status. Laboratory assessments included inflammatory markers (IL-1β, IL-6, IL-8, and TNF-α).

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Article Synopsis
  • In Alzheimer's disease, amyloid beta (Aβ) triggers the cleavage of the TrkB-FL receptor, disrupting essential BDNF signaling that is crucial for neuron health and function.
  • Researchers found that TrkB-FL cleavage occurs early in the disease and worsens with increased pathology, using human samples and cerebrospinal fluid for their studies.
  • They developed a TAT-TrkB peptide that successfully prevents TrkB-FL cleavage, showing potential in improving cognitive function and synaptic issues in a mouse model of Alzheimer's, indicating it could be a safe and effective treatment option.
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This study builds on the affective events theory and the conservation of resources theory to propose a model that analyses an affect-to-behaviour-to-outcome route, highlighting how daily micro-events and subsequent affective reactions lead to behaviours (performance) and cognitions (satisfaction after work), and how mental health moderates this process. Results from a 5-day diary study, during the pandemic (N = 250, n = 1221), provided data to test the proposed affect-to-behaviour-to-outcome route. Poorer mental health buffered the positive within-person relationship between daily micro-events, affective reactions, performance and satisfaction after work, suggesting that high levels of mental health allowed individuals to maximise the benefits of positive daily micro-events in their satisfaction after work via affect and performance.

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Macrodactyly, a often congenital anomaly, entails abnormal enlargement of digits, predominantly affecting hands or feet, either in isolation or as part of a syndromic condition. The authors present a case of Macrodystrophia Lipomatosa (ML), a form of macrodactyly, in a 62-year-old patient, emphasizing macrodactyly manifestations through clinical and radiological assessments. Additionally, the authors explore anatomical aspects related to nerve distribution in affected digits, providing a comprehensive understanding of ML.

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Objectives: In this study, we expand on the existing work on daily performance by focusing on (1) within-person fluctuation in perceived manager effectiveness in relation to daily positive affective experiences and daily performance and (2) between-person fluctuations in uncertainty as a relevant boundary condition of these relationships.

Methods: Multilevel data from 101 managers (1,010 measurement occasions) were used to test the hypotheses.

Results: The results showed that fluctuations in the perception of a manager's effectiveness related positively to daily positive affective experiences, and this relationship was moderated by the team member's uncertainty levels in such a way that perceived uncertainty buffered the positive effect of leadership effectiveness on positive affective experiences.

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Drawing on the integrative model of uncertainty tolerance, we aimed to investigate whether uncertainty relates to adaptive performance, at the within-person level. We argue that daily uncertainty at work will trigger negative affective reactions that, in turn, will minimize adaptive performance. Moreover, we focus on socio-cognitive mindfulness as a cross-level moderator of the indirect relationship of uncertainty on adaptive performance via negative affect.

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The COVID-19 crisis has had significant impacts on mental health. Students are dealing with an uncertain context, not only due to COVID-19 but also because most of them have never been involved with the challenges of online school. The COVID-19 situation presents daily challenges that require students to respond adaptively.

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This study aimed to (1) analyze the relationship between the three job crafting dimensions (task, cognitive and relational crafting) and performance; (2) explore whether meaningful work fully mediates the links between the three job crafting dimensions and performance; (3) analyze if presenteeism moderates the indirect effect of meaningful work in the relationship between job crafting and performance. To achieve these goals, we collected data with 146 workers from a town hall. We analyzed the proposed moderated-mediation model using the PROCESS macro.

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Endometrial cancer is the eighth most common cancer worldwide, and its prognosis depends on various factors, with myometrial invasion having a major impact on prognosis. Optimizing MRI protocols is essential, and it would be useful to improve the diagnostic accuracy without the need for other sequences. We conducted a retrospective, single-center study, which included a total of 87 patients with surgically confirmed primary endometrial cancer, and who had undergone a pre-operative pelvic MRI.

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Although there are many studies of leadership in military teams, few have focused on military team factors that could be linked to shared leadership in an international military staff. The focus of shared leadership is on team members' interacting in order to lead collectively by sharing leadership tasks, rather than on an individual being a sole leader. The aim of this study is to identify predictors of a positive attitude toward shared leadership in the context of military teams, and how they are related to perceived team effectiveness.

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Prolonged immobilization and, in particular, mechanical ventilation, have been linked to muscle atrophy. Anecdotal reports in the literature describe rhabdomyolysis as a potential late complication of COVID-19 infection which, in severe cases, may coexist with fluid collections. We report a case of a 28-year-old patient that had been recently hospitalized with SARS-CoV-2 pneumonia, with need for invasive ventilation support.

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Axial spondyloarthritis (axSpA) is a chronic inflammatory disorder that predominantly involves the axial skeleton. Imaging findings of axSpA can be divided into active changes, which include bone marrow edema, synovitis, enthesitis, capsulitis, and intra-articular effusion, and structural changes, which include erosions, sclerosis, bone fatty infiltration, fat deposition in an erosion cavity, and bone bridging or ankylosis. The ability to distinguish between imaging lesions suggestive of axSpA and artifacts or lesions suggestive of other disorders is critical for the accurate diagnosis of axSpA.

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Purpose Of Review: Femoroacetabular impingement (FAI) is one of the main causes of hip pain in young adults and poses clinical challenges which have placed it at the forefront of imaging and orthopedics. Diagnostic hip imaging has dramatically changed in the past years, with the arrival of new imaging techniques and the development of magnetic resonance imaging (MRI). This article reviews the current state-of-the-art clinical routine of individuals with suspected FAI, limitations, and future directions that show promise in the field of musculoskeletal research and are likely to reshape hip imaging in the coming years.

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Purpose: Analyze the impact of endovascular revascularization on major amputation rates and wound healing for patients with diabetic foot ulcers (DFUs).

Materials And Methods: Single-center retrospective study from 2014-2018 including 314 patients with DFUs submitted to endovascular revascularizations. Group A-patients with a successful endovascular revascularization (n = 285; 90.

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Anatomical variation of neuromuscular structures of the gluteal region is common. The piriformis muscle, in particular, has an important relationship with the sciatic nerve and may be associated with distinct clinical conditions. We report an incidental finding of unilateral piriformis muscle agenesis diagnosed on computed tomography and magnetic resonance imaging, a rare anatomical variant of the gluteal region.

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SAPHO (synovitis, acne, pustulosis, hyperostosis and osteitis) syndrome is a heterogeneous condition combining osteoarticular and cutaneous manifestations. Conventional treatments are mostly ineffective. We hereby report two patients, the first with an aggressive form of disease and the second with an incomplete response to two different anti-TNF-α agents.

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Article Synopsis
  • Myopathies are diverse skeletal muscle disorders involving changes like replacement of muscle tissue with connective tissue, fatty infiltration, and inflammation, and are categorized into hereditary, acquired idiopathic, and secondary types.
  • Diagnosing these conditions is complex due to similar symptoms and often requires a combination of methods, including advanced imaging techniques.
  • Whole-body MRI plays a crucial role in diagnosing myopathies by helping identify patterns of muscle involvement, guiding muscle biopsies, and assisting in ongoing disease management.
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The concept of hip impingement and hip-preserving surgery has been appreciated in more detail since 2001 when a new surgical approach was reported and a hypothesis linking femoroacetabular impingement (FAI) with osteoarthritis was presented. Paralleling the introduction of hip arthroscopy, these events led to an increasing interest in the hip, and the number of publications has risen rapidly over the past 15 years, despite limited evidence levels and inconsistent methodology. Accordingly, etiology, diagnosis, prognosis, and the effects of treatment for FAI are still elusive due to a number of uncertainties and a lack of clear diagnostic criteria.

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Sudden respiratory distress in association with severe weight loss are unusual features of systemic sclerosis (SSc). We report the case of a 56-year-old Caucasian woman with a 9-year history of a diffuse form of SSc who presented with acute stridor due to vocal cord paralysis and required an emergency tracheostomy. She had sought medical attention only after 4 years of disease onset, presenting with a mask-like face, diffuse skin thickening, acro-osteolysis and severe interstitial lung disease.

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Background: Given the high prevalence of patients with hip deformities and no ongoing hip dysfunction, understanding the anatomic factors predicting the symptomatic state is critical. One such variable is how the spinopelvic parameters (SPPs) may interplay with hip anatomic factors.

Hypothesis/purpose: SPPs and femoral- and acetabular-specific parameters may predict which patients will become symptomatic.

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The Psychological Capital Questionnaire (PCQ) is the most commonly used measure for assessing psychological capital in work settings. Although several studies confirmed its factorial validity, most validation studies only examined the four-factor structure preconized by Luthans, Youssef, and Avolio, not attending to empirical evidence on alternative factorial structures. The present study aimed to test the psychometric properties of the Portuguese version of the PCQ, by using two independent samples (NS1 = 542; NS2 = 115) of Portuguese employees.

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Brain-derived neurotrophic factor (BDNF) and its high-affinity full-length (FL) receptor, TrkB-FL, play a central role in the nervous system by providing trophic support to neurons and regulating synaptic plasticity and memory. TrkB and BDNF signaling are impaired in Alzheimer's disease (AD), a neurodegenerative disease involving accumulation of amyloid-β (Aβ) peptide. We recently showed that Aβ leads to a decrease of TrkB-FL receptor and to an increase of truncated TrkB receptors by an unknown mechanism.

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This manuscript examined the psychometric properties and factor structure of the emotional contagion scale in a Portuguese sample. The original scale was first given to a sample of 1445 individuals to verify its internal consistency. Both exploratory and confirmatory factor analyses were performed.

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