Publications by authors named "Antonio Amadu"

Article Synopsis
  • The study investigated the impact of COVID-19 on patients with beta-thalassemia major, revealing that while prevalence is slightly lower, mortality rates are higher compared to the general population.
  • Out of 68 enrolled patients, only 5 tested positive for COVID-19, with no significant complications or hospitalizations reported, indicating a relatively mild course of the disease in this patient group.
  • Vaccination resulted in a strong antibody response, particularly among those who were previously infected, suggesting that beta-thalassemia major patients may have a lower risk of severe COVID-19 than initially thought.
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Article Synopsis
  • * This retrospective study included 232 patients who had surgery for acute appendicitis and underwent preoperative CT scans, classifying appendicitis into 5 severity grades.
  • * Results showed a strong correlation between CT and surgical findings, with most patients having grade 1 and 2 appendicitis treated laparoscopically, while the approach varied for higher grades, indicating CT staging may guide surgical decisions effectively.
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Background: Cardiac magnetic resonance (CMR) with late gadolinium enhancement (LGE) is a key diagnostic tool in the differential diagnosis between non-ischemic cause of cardiac chest pain. Some patients are not eligible for a gadolinium contrast-enhanced CMR; in this scenario, the diagnosis remains challenging without invasive examination. Our purpose was to derive a machine learning model integrating some non-contrast CMR parameters and demographic factors to identify Takotsubo cardiomyopathy (TTC) in subjects with cardiac chest pain.

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We investigate the impact of dipper status on cardiac structure with cardiovascular magnetic resonance (CMR). Ambulatory blood pressure monitoring and 1.5T CMR were performed in 99 tertiary hypertension clinic patients.

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We present the case of a 62 year-old woman who was admitted to our institute of radiological sciences for a breast mass developed in the last few months. The final diagnosis was primary breast chondrosarcoma and the surgical treatment performed, based on imaging and pathological findings, was the mastectomy.

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Aims: In hypertension, the presence of left ventricular (LV) strain pattern on 12-lead electrocardiogram (ECG) carries adverse cardiovascular prognosis. The underlying mechanisms are poorly understood. We investigated whether hypertensive ECG strain is associated with myocardial interstitial fibrosis and impaired myocardial strain, assessed by multi-parametric cardiac magnetic resonance (CMR).

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Objective: Myocardial intracellular/extracellular structure and aortic function were assessed among hypertensive left ventricular (LV) phenotypes using cardiovascular magnetic resonance (CMR).

Methods: An observational study from consecutive tertiary hypertension clinic patients referred for CMR (1.5 T) was performed.

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Cardiovascular magnetic resonance (CMR) is an established non-invasive technique to comprehensively assess cardiovascular structure and function in a variety of acquired and inherited cardiac conditions. A significant amount of the neck, thorax and upper abdomen are imaged at the time of routine clinical CMR, particularly in the initial multi-slice axial and coronal images. The discovery of unsuspected disease at the time of imaging has ethical, financial and medico-legal implications.

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Aims: We sought to determine the prevalence of asymmetric hypertensive heart disease (HHD) overlapping morphologically with hypertrophic cardiomyopathy (HCM) and to determine predictors of this pattern of hypertensive remodelling.

Methods And Results: One hundred and fifty hypertensive patients underwent 1.5 T cardiovascular magnetic resonance imaging.

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