Publications by authors named "Antonio Albaya-Moreno"
Objective: To validate the unsupervised cluster model (USCM) developed during the first pandemic wave in a cohort of critically ill patients from the second and third pandemic waves.
Design: Observational, retrospective, multicentre study.
Setting: Intensive Care Unit (ICU).
Objective: To evaluate the impact of obesity on ICU mortality.
Design: Observational, retrospective, multicentre study.
Setting: Intensive Care Unit (ICU).
Article Synopsis
- The study investigates the timing of intubation in patients with SARS-CoV-2 pneumonia, suggesting that delaying intubation increases the risk of mortality, especially in cases of acute respiratory failure.
- Data from 4,198 patients across 73 ICUs revealed that patients who were intubated earlier (within 24 hours) experienced lower mortality rates compared to those who were intubated later (37% vs. 32%).
- The findings support early intubation as a protective factor against death in COVID-19 pneumonia patients, emphasizing the importance of timely intervention in critical care settings.
Risk factors for developing ventilator-associated lower respiratory tract infection in patients with severe COVID-19: a multinational, multicentre study, prospective, observational study.
Sci Rep
April 2023
Around one-third of patients diagnosed with COVID-19 develop a severe illness that requires admission to the Intensive Care Unit (ICU). In clinical practice, clinicians have learned that patients admitted to the ICU due to severe COVID-19 frequently develop ventilator-associated lower respiratory tract infections (VA-LRTI). This study aims to describe the clinical characteristics, the factors associated with VA-LRTI, and its impact on clinical outcomes in patients with severe COVID-19.
View Article and Find Full Text PDFPurpose: Dexamethasone is the only drug that has consistently reduced mortality in patients with COVID-19, especially in patients needing oxygen or invasive mechanical ventilation. However, there is a growing concern about the relation of dexamethasone with the unprecedented rates of ICU-acquired respiratory tract infections (ICU-RTI) observed in patients with severe COVID-19.
Methods: This was a multicenter, prospective cohort study; conducted in ten countries in Latin America and Europe.
Article Synopsis
- The study aimed to evaluate the impact of corticosteroids on ICU mortality in mechanically ventilated COVID-19 patients suffering from ARDS.
- Conducted in 70 ICUs, the study included 1,835 patients, with 1,117 receiving corticosteroids; however, initial results showed no significant difference in ICU mortality between those treated and those untreated with corticosteroids.
- While corticosteroid treatment appeared to provide short-term survival benefits, it led to increased ICU mortality after 17 days, particularly benefiting younger patients and those with severe ARDS.
Deploying unsupervised clustering analysis to derive clinical phenotypes and risk factors associated with mortality risk in 2022 critically ill patients with COVID-19 in Spain.
Crit Care
February 2021
Background: The identification of factors associated with Intensive Care Unit (ICU) mortality and derived clinical phenotypes in COVID-19 patients could help for a more tailored approach to clinical decision-making that improves prognostic outcomes.
Methods: Prospective, multicenter, observational study of critically ill patients with confirmed COVID-19 disease and acute respiratory failure admitted from 63 ICUs in Spain. The objective was to utilize an unsupervised clustering analysis to derive clinical COVID-19 phenotypes and to analyze patient's factors associated with mortality risk.