Efficacy of a brief multifactorial adherence-based intervention in reducing blood pressure: a randomized clinical trial.

Background: Lowering blood pressure (BP) by antihypertensive (AHT) drugs reduces the risks of cardiovascular events, stroke, and total mortality. However, poor adherence to AHT medications reduces their effectiveness and increases the risk of adverse events.

Objective: To evaluate the effectiveness of a multifactorial adherence-based intervention in a primary care setting in lowering BP.

Relationship of diagnostic and therapeutic delay with survival in colorectal cancer: a review.

Background: Early diagnosis of colorectal cancer before the onset of symptoms improves survival. Once symptoms have occurred, however, the effect of delay on survival is unclear. We review here evidence on the relationship of diagnostic and therapeutic delay with survival in colorectal cancer.