Publications by authors named "Antonina I Tretyakova"
Article Synopsis
- Antimicrobial photodynamic therapy (APDT) utilizes light-activated compounds called photosensitizers to combat antibiotic-resistant bacteria.
- This study tested various plant extracts as photosensitizers against gram-negative (Pseudomonas aeruginosa) and gram-positive (Staphylococcus aureus) bacteria, showing them to be effective in generating singlet oxygen for bacterial inactivation.
- The results indicated that exposing P. aeruginosa to 405 nm light produced a significant reduction in bacterial counts, while S. aureus showed a similar effectiveness across all tested light wavelengths and doses.
Identification by methods of steady-state and kinetic spectrofluorimetry of endogenous porphyrins and flavins sensitizing the formation of reactive oxygen species in cancer cells.
Vitaly Yu Plavskii Andrei N Sobchuk Aliaksandr V Mikulich Olga N Dudinova Ludmila G Plavskaya Antonina I Tretyakova
Photochem Photobiol
September 2024
The question about acceptor molecules of optical radiation that determine the effects of photobiomodulation in relation to various types of cells still remains the focus of attention of researchers. This issue is most relevant for cancer cells, since, depending on the parameters of optical radiation, light can either stimulate their growth or inhibit them and lead to death. This study shows that endogenous porphyrins, which have sensitizing properties, may play an important role in the implementation of the effects of photobiomodulation, along with flavins.
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