Biomarkers of oxidative stress and smoking in cancer patients.

Context: Increased oxidative stress is a significant part of pathogenesis of smoking-related cancer.

Aim: The study aims to investigate changes in antioxidant status induced by chronic cigarette smoking in cancer patients and healthy subjects.

Setting And Design: We examined the venous blood samples of 54 healthy subjects, both smokers (25) and non-smokers and of 50 patients with smoking-related cancer, both smokers (34) and non-smokers.