Publications by authors named "Antonia Sanchez-Bautista"
Unlabelled: Rapid microbiological diagnosis of the antibiotic susceptibility of Gram-negative bacilli is a priority in clinical microbiology, especially in cases of bacteremia. The rapid advancement of antimicrobial resistance proposes a challenge for empirical antibiotic therapy and shows the need for fast antibiotic susceptibility diagnostics to guide treatments. The QuickMIC System (Gradientech AB, Uppsala, Sweden) is a recently developed rapid diagnostic tool for antibiotic susceptibility testing.
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- Carbapenem-resistant infections are a serious public health issue, necessitating the development of new antibiotics, like cefiderocol, which has shown strong effectiveness against resistant strains.
- A study of 109 strains from a Spanish hospital demonstrated high susceptibility to cefiderocol, with only 2 strains being resistant, and it outperformed other antibiotics, supported by consistent testing methods.
- While cefiderocol shows promise as a treatment, there is concern about drug resistance and the need for careful antibiotic use and ongoing resistance monitoring, highlighting the relationship between bacterial load and drug effectiveness.
Background: shows resistance to several antibiotics and often develops such resistance during patient treatment.
Objective: Develop an in vitro model, using clinical isolates of , to compare the ability of the imipenem and imipenem/relebactam to generate resistant mutants to imipenem and to other antibiotics. Perform a genotypic analysis to detect how the selective pressure changes their genomes.
Hemolytic anemia in pediatric patients treated with artesunate for severe malaria.
Enferm Infecc Microbiol Clin (Engl Ed)
March 2020
Airway microbiota in patients with paediatric cystic fibrosis: Relationship with clinical status.
Enferm Infecc Microbiol Clin (Engl Ed)
March 2019
Introduction: New massive sequencing techniques make it possible to determine the composition of airway microbiota in patients with cystic fibrosis (CF). However, the relationship between the composition of lung microbiome and the clinical status of paediatric patients is still not fully understood.
Material And Methods: A cross-sectional observational study was conducted on induced sputum samples from children with CF and known mutation in the CFTR gene.
From CLSI to EUCAST guidelines in the interpretation of antimicrobial susceptibility: What is the effect in our setting?
Enferm Infecc Microbiol Clin (Engl Ed)
April 2018
Introduction: Implementation of the breakpoints established in the European Committee on Antimicrobial Susceptibility Testing (EUCAST) guidelines in comparison with those of the Clinical and Laboratory Standards Institute (CLSI) means that the criteria for interpreting the susceptibility of some antimicrobials have been modified, resulting in changes in the reports of accumulated antibiotic susceptibility.
Methods: The effect of applying EUCAST breakpoints in 10,359 clinical isolates of Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus spp. was analysed.