Publications by authors named "Antonia Maria Miro"
J Cell Biochem
October 2012
Article Synopsis
- The study explores how the hormone 17beta-estradiol (E2) affects oxidative stress and certain proteins in breast cancer cells, focusing on estrogen receptors ERalpha and ERbeta.
- In breast tumors, the ratio of ERalpha to ERbeta is higher compared to normal tissue, which may influence how these cells respond to oxidative stress.
- The research found that cell lines with different ERalpha/ERbeta ratios (like T47D and MCF-7) exhibited distinct responses: T47D had low reactive oxygen species (ROS) and high UCP5, while MCF-7 showed high oxidative stress along with increased antioxidant enzyme levels, but decreased UCP2 and worsening oxidative damage.
