Disentangling the Frequency Content in Optoacoustics.

Signals acquired by optoacoustic tomography systems have broadband frequency content that encodes information about structures on different physical scales. Concurrent processing and rendering of such broadband signals may result in images with poor contrast and fidelity due to a bias towards low frequency contributions from larger structures. This problem cannot be addressed by filtering different frequency bands and reconstructing them individually, as this procedure leads to artefacts due to its incompatibility with the entangled frequency content of signals generated by structures of different sizes.

Assessment of hessian-based Frangi vesselness filter in optoacoustic imaging.

The Hessian-based Frangi vesselness filter is commonly used to enhance vasculature in optoacoustic (photoacoustic) images, but its accuracy and limitations have never been rigorously assessed. Here we validate the ability of the filter to enhance vessel-like structures in phantoms, and we introduce an experimental approach that uses measurements before and after the administration of gold nanorods (AuNRs) to examine filter performance . We evaluate the influence of contrast, filter scales, angular tomographic coverage, out-of-plane signals and light fluence on image quality, and gain insight into the performance of the filter.

Vibration Testing Procedures for Bone Stiffness Assessment in Fractures Treated with External Fixation.

A bone healing assessment is crucial for the successful treatment of fractures, particularly in terms of the timing of support devices. However, in clinical practice, this assessment is only made qualitatively through bone manipulation and X-rays, and hence cannot be repeated as often as might be required. The present study reconsiders the quantitative method of frequency response analysis for healing assessments, and specifically for fractures treated with an external fixator.