Publications by authors named "Antonia Chatziliami"

Hereditary hemolytic disorders cause ineffective erythropoiesis and bone marrow hyperplasia. Little is known about their effect on growth and skeletal health. The aim of this study was to evaluate growth, bone and body composition of non transfusion-dependent (NTD) pediatric patients with chronic hemolysis.

View Article and Find Full Text PDF

Objective: Bone tissue is adversely affected in patients with homozygous β-thalassemia. The aim of this study was to find warning signs of bone loss in young patients with β-thalassemia and allow prompt therapeutic interventions.

Methods: Thirty-eight patients were studied, 20 boys and 18 girls, aged 5 to 18 years (median = 14.

View Article and Find Full Text PDF

Purpose: To evaluate whether the introduction of magnetic resonance imaging (MRI) in the management of thalassemia major (TM) patients has affected the risk of cardiac death.

Materials And Methods: In all, 804 TM patients from two large reference units were included and the risk of dying of cardiac causes, before and after their first MRI, was assessed by a Cox proportional hazards model with time-dependent covariates.

Results: Adding information from MRI reduced the risk of cardiac death from 6.

View Article and Find Full Text PDF

Background: With transfusions and chelation therapy, the prognosis for transfusion-dependent beta thalassaemia has changed from being fatal in early childhood to a chronic disorder with prolonged survival.

Design And Methods:   In this historical prospective study, we present survival, causes of death and mortality ratios compared to the general population in 1044 Greek patients with transfusion-dependent beta thalassaemia.

Results:   At the age of 50years, the overall survival was 65.

View Article and Find Full Text PDF